Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
1R01ES004311-01
Application #
3252373
Study Section
Toxicology Study Section (TOX)
Project Start
1987-06-01
Project End
1992-05-31
Budget Start
1987-06-01
Budget End
1988-05-31
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
Schools of Veterinary Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Carratt, S A; Morin, D; Buckpitt, A R et al. (2016) Naphthalene cytotoxicity in microsomal epoxide hydrolase deficient mice. Toxicol Lett 246:35-41
Pham, Nathalie T; Jewell, William T; Morin, Dexter et al. (2012) Analysis of naphthalene adduct binding sites in model proteins by tandem mass spectrometry. Chem Biol Interact 199:120-8
Pham, Nathalie T; Jewell, William T; Morin, Dexter et al. (2012) Characterization of model peptide adducts with reactive metabolites of naphthalene by mass spectrometry. PLoS One 7:e42053
Li, Lei; Wei, Yuan; Van Winkle, Laura et al. (2011) Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa. J Pharmacol Exp Ther 339:62-71
Spiess, Page C; Morin, Dexter; Williams, Chase R et al. (2010) Protein thiol oxidation in murine airway epithelial cells in response to naphthalene or diethyl maleate. Am J Respir Cell Mol Biol 43:316-25
Lin, Ching Yu; Wheelock, Asa M; Morin, Dexter et al. (2009) Toxicity and metabolism of methylnaphthalenes: comparison with naphthalene and 1-nitronaphthalene. Toxicology 260:16-27
Spiess, Page C; Morin, Dexter; Jewell, William T et al. (2008) Measurement of protein sulfhydryls in response to cellular oxidative stress using gel electrophoresis and multiplexed fluorescent imaging analysis. Chem Res Toxicol 21:1074-85
Lee, Myong Gyong; Wheelock, Asa M; Boland, Bridget et al. (2008) Long-term ozone exposure attenuates 1-nitronaphthalene-induced cytotoxicity in nasal mucosa. Am J Respir Cell Mol Biol 38:300-9
Morisseau, Christophe; Newman, John W; Wheelock, Craig E et al. (2008) Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chem Res Toxicol 21:951-7
Lin, Ching Yu; Boland, Bridget C; Lee, Young Jin et al. (2006) Identification of proteins adducted by reactive metabolites of naphthalene and 1-nitronaphthalene in dissected airways of rhesus macaques. Proteomics 6:972-82

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