Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES006376-04
Application #
2155242
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1993-06-01
Project End
1997-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Pharmacology
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Sakurai, Toshiharu; Kudo, Masatoshi; Umemura, Atsushi et al. (2013) p38? inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of reactive oxygen species. Cancer Res 73:215-24
Du, Hongjun; Sun, Xufang; Guma, Monica et al. (2013) JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular degeneration. Proc Natl Acad Sci U S A 110:2377-82
Lee, Jun Hee; Budanov, Andrei V; Talukdar, Saswata et al. (2012) Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metab 16:311-21
Guma, Monica; Hammaker, Deepa; Topolewski, Katharyn et al. (2012) Antiinflammatory functions of p38 in mouse models of rheumatoid arthritis: advantages of targeting upstream kinases MKK-3 or MKK-6. Arthritis Rheum 64:2887-95
Aghajan, Mariam; Li, Ning; Karin, Michael (2012) Obesity, autophagy and the pathogenesis of liver and pancreatic cancers. J Gastroenterol Hepatol 27 Suppl 2:10-4
Sun, Beicheng; Karin, Michael (2012) Obesity, inflammation, and liver cancer. J Hepatol 56:704-13
Ali, Syed Raza; Timmer, Anjuli M; Bilgrami, Sameera et al. (2011) Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage. Immunity 35:34-44
Holzer, Ryan G; Park, Eek-Joong; Li, Ning et al. (2011) Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. Cell 147:173-84
Lee, Jun Hee; Bodmer, Rolf; Bier, Ethan et al. (2010) Sestrins at the crossroad between stress and aging. Aging (Albany NY) 2:369-74
Guma, Monica; Kashiwakura, Jun-ichi; Crain, Brian et al. (2010) JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis. Proc Natl Acad Sci U S A 107:22122-7

Showing the most recent 10 out of 54 publications