Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES006478-03
Application #
2155327
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1994-09-15
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Midwestern University
Department
Pharmacology
Type
Schools of Osteopathy
DUNS #
181778846
City
Downers Grove
State
IL
Country
United States
Zip Code
60515
Edwards, Joshua R; Kolman, Kevin; Lamar, Peter C et al. (2013) Effects of cadmium on the sub-cellular localization of ?-catenin and ?-catenin-regulated gene expression in NRK-52E cells. Biometals 26:33-42
Prozialeck, Walter C; Edwards, Joshua R (2012) Mechanisms of cadmium-induced proximal tubule injury: new insights with implications for biomonitoring and therapeutic interventions. J Pharmacol Exp Ther 343:2-12
Prozialeck, Walter C; Edwards, Joshua R (2010) Early biomarkers of cadmium exposure and nephrotoxicity. Biometals 23:793-809
Prozialeck, Walter C; Edwards, Joshua R; Lamar, Peter C et al. (2009) Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury. Toxicol Appl Pharmacol 238:306-14
Vaidya, Vishal S; Ford, Glen M; Waikar, Sushrut S et al. (2009) A rapid urine test for early detection of kidney injury. Kidney Int 76:108-14
Edwards, Joshua R; Prozialeck, Walter C (2009) Cadmium, diabetes and chronic kidney disease. Toxicol Appl Pharmacol 238:289-93
Prozialeck, Walter C; Edwards, Joshua R; Vaidya, Vishal S et al. (2009) Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity. Toxicol Appl Pharmacol 238:301-5
Prozialeck, Walter C; Edwards, Joshua R; Nebert, Daniel W et al. (2008) The vascular system as a target of metal toxicity. Toxicol Sci 102:207-18
Woods, J M; Leone, M; Klosowska, K et al. (2008) Direct antiangiogenic actions of cadmium on human vascular endothelial cells. Toxicol In Vitro 22:643-51
Prozialeck, Walter C; Edwards, Joshua R (2007) Cell adhesion molecules in chemically-induced renal injury. Pharmacol Ther 114:74-93

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