Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES007062-02
Application #
2156145
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1995-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Guilarte, Tomás R (2018) TSPO in diverse CNS pathologies and psychiatric disease: A critical review and a way forward. Pharmacol Ther :
Rubin, Leah H; Sacktor, Ned; Creighton, Jason et al. (2018) Microglial activation is inversely associated with cognition in individuals living with HIV on effective antiretroviral therapy. AIDS 32:1661-1667
Coughlin, Jennifer M; Wang, Yuchuan; Minn, Il et al. (2017) Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players. JAMA Neurol 74:67-74
Guilarte, Tomás R; Loth, Meredith K; Guariglia, Sara R (2016) TSPO Finds NOX2 in Microglia for Redox Homeostasis. Trends Pharmacol Sci 37:334-343
Cole, Toby B; Coburn, Jacki; Dao, Khoi et al. (2016) Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain. Toxicology 374:1-9
Loth, Meredith K; Choi, Judy; McGlothan, Jennifer L et al. (2016) TSPO in a murine model of Sandhoff disease: presymptomatic marker of neurodegeneration and disease pathophysiology. Neurobiol Dis 85:174-186
Wegrzynowicz, Michal; Bichell, Terry Jo; Soares, Barbara D et al. (2015) Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype. J Huntingtons Dis 4:17-36
Coughlin, Jennifer M; Wang, Yuchuan; Munro, Cynthia A et al. (2015) Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study. Neurobiol Dis 74:58-65
D'Agostino, Jaime; Zhang, Haoming; Kenaan, Cesar et al. (2015) Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos. Chem Res Toxicol 28:1484-95
Coughlin, Jennifer M; Wang, Yuchuan; Ma, Shuangchao et al. (2014) Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV. J Neurovirol 20:219-32

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