Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
3R01ES008075-01S1
Application #
2468864
Study Section
Reproductive Biology Study Section (REB)
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Radiation-Diagnostic/Oncology
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Shetty, G; Zhou, W; Weng, C C Y et al. (2016) Leydig cells contribute to the inhibition of spermatogonial differentiation after irradiation of the rat. Andrology 4:412-24
Sahin, Z; Szczepny, A; McLaughlin, E A et al. (2014) Dynamic Hedgehog signalling pathway activity in germline stem cells. Andrology 2:267-74
Meistrich, Marvin L (2013) Effects of chemotherapy and radiotherapy on spermatogenesis in humans. Fertil Steril 100:1180-6
Abuelhija, M; Weng, C C; Shetty, G et al. (2013) Rat models of post-irradiation recovery of spermatogenesis: interstrain differences. Andrology 1:206-15
Abuelhija, Mahmoud; Weng, Connie C; Shetty, Gunapala et al. (2012) Differences in radiation sensitivity of recovery of spermatogenesis between rat strains. Toxicol Sci 126:545-53
Drumond, Ana Luiza; Weng, Connie C; Wang, Gensheng et al. (2011) Effects of multiple doses of cyclophosphamide on mouse testes: accessing the germ cells lost, and the functional damage of stem cells. Reprod Toxicol 32:395-406
Zhou, Wei; Bolden-Tiller, Olga U; Shao, Shan H et al. (2011) Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation. Biol Reprod 85:823-33
Zhou, Wei; Bolden-Tiller, Olga U; Shetty, Gunapala et al. (2010) Changes in gene expression in somatic cells of rat testes resulting from hormonal modulation and radiation-induced germ cell depletion. Biol Reprod 82:54-65
Wang, Gensheng; Shao, Shan H; Weng, Connie C Y et al. (2010) Hormonal suppression restores fertility in irradiated mice from both endogenous and donor-derived stem spermatogonia. Toxicol Sci 117:225-37
Porter, Karen L; Shetty, Gunapala; Shuttlesworth, Gladis A et al. (2009) Estrogen enhances recovery from radiation-induced spermatogonial arrest in rat testes. J Androl 30:440-51

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