Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
1R01ES008263-01
Application #
2157645
Study Section
Special Emphasis Panel (ZES1-CKS-B (M1))
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Organized Research Units
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Park, In Young; Powell, Reid T; Tripathi, Durga Nand et al. (2016) Dual Chromatin and Cytoskeletal Remodeling by SETD2. Cell 166:950-962
Treviño, Lindsey S; Wang, Quan; Walker, Cheryl L (2015) Phosphorylation of epigenetic ""readers, writers and erasers"": Implications for developmental reprogramming and the epigenetic basis for health and disease. Prog Biophys Mol Biol 118:8-13
Treviño, Lindsey S; Wang, Quan; Walker, Cheryl L (2015) Hypothesis: Activation of rapid signaling by environmental estrogens and epigenetic reprogramming in breast cancer. Reprod Toxicol 54:136-40
Wong, Rebecca Lee Yean; Walker, Cheryl Lyn (2013) Molecular pathways: environmental estrogens activate nongenomic signaling to developmentally reprogram the epigenome. Clin Cancer Res 19:3732-7
Greathouse, K Leigh; Bredfeldt, Tiffany; Everitt, Jeffrey I et al. (2012) Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis. Mol Cancer Res 10:546-57
Walker, Cheryl Lyn; Ho, Shuk-mei (2012) Developmental reprogramming of cancer susceptibility. Nat Rev Cancer 12:479-86
Walker, Cheryl Lyn (2011) Epigenomic reprogramming of the developing reproductive tract and disease susceptibility in adulthood. Birth Defects Res A Clin Mol Teratol 91:666-71
Short, John D; Dere, Ruhee; Houston, Kevin D et al. (2010) AMPK-mediated phosphorylation of murine p27 at T197 promotes binding of 14-3-3 proteins and increases p27 stability. Mol Carcinog 49:429-39
McCampbell, Adrienne S; Broaddus, Russell R; Walker, Cheryl L (2010) Loss of inhibitory insulin receptor substrate-1 phosphorylation: An early event in endometrial hyperplasia and progression to carcinoma. Cell Cycle 9:2698-9
McCampbell, Adrienne S; Harris, Heather A; Crabtree, Judy S et al. (2010) Loss of inhibitory insulin receptor substrate-1 phosphorylation is an early event in mammalian target of rapamycin-dependent endometrial hyperplasia and carcinoma. Cancer Prev Res (Phila) 3:290-300

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