Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY000459-27
Application #
2684459
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1977-05-01
Project End
1998-06-30
Budget Start
1998-04-01
Budget End
1998-06-30
Support Year
27
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Rochester
Department
Ophthalmology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Zigman, S; McDaniel, T; Schultz, J et al. (2000) Effects of intermittent UVA exposure on cultured lens epithelial cells. Curr Eye Res 20:95-100
Atherton, S J; Lambert, C; Schultz, J et al. (1999) Fluorescence studies of lens epithelial cells and their constituents. Photochem Photobiol 70:823-8
Zigman, S; Schultz, J B; Schultz, M (1998) Measurement of oxygen production by in vitro human and animal lenses with an oxygen electrode. Curr Eye Res 17:115-9
DeMott, M S; Zigman, S; Bambara, R A (1998) Replication protein A stimulates long patch DNA base excision repair. J Biol Chem 273:27492-8
Rafferty, N S; Rafferty, K A; Zigman, S (1997) Comparative response to UV irradiation of cytoskeletal elements in rabbit and skate lens epithelial cells. Curr Eye Res 16:310-9
DeMott, M S; Shen, B; Park, M S et al. (1996) Human RAD2 homolog 1 5'- to 3'-exo/endonuclease can efficiently excise a displaced DNA fragment containing a 5'-terminal abasic lesion by endonuclease activity. J Biol Chem 271:30068-76
Zigman, S; Reddan, J; Schultz, J B et al. (1996) Structural and functional changes in catalase induced by near-UV radiation. Photochem Photobiol 63:818-24
Zigman, S; McDaniel, T; Schultz, J B et al. (1995) Damage to cultured lens epithelial cells of squirrels and rabbits by UV-A (99.9%) plus UV-B (0.1%) radiation and alpha tocopherol protection. Mol Cell Biochem 143:35-46
Zigman, S (1995) Environmental near-UV radiation and cataracts. Optom Vis Sci 72:899-901
Zigman, S; Rafferty, N S; Schultz, M (1995) Dogfish (Mustelus canis) lens catalase reduces H2O2-induced opacification. Biol Bull 189:222-3

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