Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
3R01EY001919-12S1
Application #
3256336
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1978-07-01
Project End
1989-07-31
Budget Start
1987-07-01
Budget End
1989-07-31
Support Year
12
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
LaVail, Matthew M; Nishikawa, Shimpei; Steinberg, Roy H et al. (2018) Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration. Exp Eye Res 167:56-90
Roddy, Gavin W; Yasumura, Douglas; Matthes, Michael T et al. (2017) Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1. Exp Eye Res 165:175-181
Stiles, Megan; Qi, Hui; Sun, Eleanor et al. (2016) Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration. J Lipid Res 57:818-31
LaVail, Matthew M; Yasumura, Douglas; Matthes, Michael T et al. (2016) Gene Therapy for MERTK-Associated Retinal Degenerations. Adv Exp Med Biol 854:487-93
Chiang, Wei-Chieh; Joseph, Victory; Yasumura, Douglas et al. (2016) Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin. Adv Exp Med Biol 854:185-91
Kohl, Susanne; Zobor, Ditta; Chiang, Wei-Chieh et al. (2015) Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. Nat Genet 47:757-65
Vollrath, Douglas; Yasumura, Douglas; Benchorin, Gillie et al. (2015) Tyro3 Modulates Mertk-Associated Retinal Degeneration. PLoS Genet 11:e1005723
Chiang, Wei-Chieh; Kroeger, Heike; Sakami, Sanae et al. (2015) Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration. Mol Neurobiol 52:679-95
Alavi, Marcel V; Chiang, Wei-Chieh; Kroeger, Heike et al. (2015) In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse. Invest Ophthalmol Vis Sci 56:6961-70
Orhan, Elise; Dalkara, Deniz; Neuillé, Marion et al. (2015) Genotypic and phenotypic characterization of P23H line 1 rat model. PLoS One 10:e0127319

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