Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY003177-17
Application #
2158725
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1991-09-30
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Sydney
Department
Type
DUNS #
752389338
City
Sydney
State
Country
Australia
Zip Code
2006
Dawes, L J; Shelley, E J; McAvoy, J W et al. (2018) A role for Hippo/YAP-signaling in FGF-induced lens epithelial cell proliferation and fibre differentiation. Exp Eye Res 169:122-133
Zhao, Guannan; Bailey, Charles G; Feng, Yue et al. (2018) Negative regulation of lens fiber cell differentiation by RTK antagonists Spry and Spred. Exp Eye Res 170:148-159
Shu, Daisy Y; Wojciechowski, Magdalena C; Lovicu, Frank J (2017) Bone Morphogenetic Protein-7 Suppresses TGF?2-Induced Epithelial-Mesenchymal Transition in the Lens: Implications for Cataract Prevention. Invest Ophthalmol Vis Sci 58:781-796
Wojciechowski, Magdalena C; Mahmutovic, Leila; Shu, Daisy Y et al. (2017) ERK1/2 signaling is required for the initiation but not progression of TGF?-induced lens epithelial to mesenchymal transition (EMT). Exp Eye Res 159:98-113
McAvoy, J W; Dawes, L J; Sugiyama, Y et al. (2017) Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape. Exp Eye Res 156:34-40
Shu, Daisy Y; Lovicu, Frank J (2017) Myofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosis. Prog Retin Eye Res 60:44-65
Das, Shannon J; Lovicu, Frank J; Collinson, Emma J (2016) Nox4 Plays a Role in TGF-?-Dependent Lens Epithelial to Mesenchymal Transition. Invest Ophthalmol Vis Sci 57:3665-73
Lovicu, F J; Shin, E H; McAvoy, J W (2016) Fibrosis in the lens. Sprouty regulation of TGF?-signaling prevents lens EMT leading to cataract. Exp Eye Res 142:92-101
Audette, Dylan S; Anand, Deepti; So, Tammy et al. (2016) Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression. Development 143:318-28
Sugiyama, Yuki; Shelley, Elizabeth J; Yoder, Bradley K et al. (2016) Non-essential role for cilia in coordinating precise alignment of lens fibres. Mech Dev 139:10-7

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