Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY004554-12A1
Application #
2159095
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1983-03-01
Project End
1998-11-30
Budget Start
1995-12-04
Budget End
1996-11-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Rapp, L M; Maple, S S; Choi, J H (2000) Lutein and zeaxanthin concentrations in rod outer segment membranes from perifoveal and peripheral human retina. Invest Ophthalmol Vis Sci 41:1200-9
Rapp, L M; Ghalayini, A J (1999) Influence of UVA light stress on photoreceptor cell metabolism: decreased rates of rhodopsin regeneration and opsin synthesis. Exp Eye Res 68:757-64
Rakoczy, P E; Lai, M C; Vijayasekaran, S et al. (1996) Initiation of impaired outer segment degradation in vivo using an antisense oligonucleotide. Curr Eye Res 15:119-23
Rapp, L M; Fisher, P L; Suh, D W (1996) Evaluation of retinal susceptibility to light damage in pigmented rats supplemented with beta-carotene. Curr Eye Res 15:219-23
Pittler, S J; Fliesler, S J; Fisher, P L et al. (1995) In vivo requirement of protein prenylation for maintenance of retinal cytoarchitecture and photoreceptor structure. J Cell Biol 130:431-9
Rapp, L M; Fisher, P L; Dhindsa, H S (1994) Reduced rate of rod outer segment disk synthesis in photoreceptor cells recovering from UVA light damage. Invest Ophthalmol Vis Sci 35:3540-8
Rapp, L M; Fisher, P L; Sheinberg, C H (1994) Impact of lipofuscin on the retinal pigment epithelium: electroretinographic evaluation of a protease inhibition model. Graefes Arch Clin Exp Ophthalmol 232:232-7
Fliesler, S J; Florman, R; Rapp, L M et al. (1993) In vivo biosynthesis of cholesterol in the rat retina. FEBS Lett 335:234-8
Rapp, L M; Smith, S C (1992) Evidence against melanin as the mediator of retinal phototoxicity by short-wavelength light. Exp Eye Res 54:55-62
Rapp, L M; Smith, S C (1992) Morphologic comparisons between rhodopsin-mediated and short-wavelength classes of retinal light damage. Invest Ophthalmol Vis Sci 33:3367-77

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