Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY005093-13
Application #
2019479
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1984-09-30
Project End
1997-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Tennessee Knoxville
Department
Microbiology/Immun/Virology
Type
Schools of Veterinary Medicine
DUNS #
City
Knoxville
State
TN
Country
United States
Zip Code
37996
Rajasagi, Naveen K; Rouse, Barry T (2018) Application of our understanding of pathogenesis of herpetic stromal keratitis for novel therapy. Microbes Infect 20:526-530
Bhela, Siddheshvar; Rouse, Barry T (2018) Are miRNAs critical determinants in herpes simplex virus pathogenesis? Microbes Infect 20:461-465
Sehrawat, Sharvan; Kumar, Dhaneshwar; Rouse, Barry T (2018) Herpesviruses: Harmonious Pathogens but Relevant Cofactors in Other Diseases? Front Cell Infect Microbiol 8:177
Varanasi, Siva Karthik; Rajasagi, Naveen K; Jaggi, Ujjaldeep et al. (2018) Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions. Mucosal Immunol 11:1705-1715
Rajasagi, Naveen K; Bhela, Siddheshvar; Varanasi, Siva Karthik et al. (2017) Frontline Science: Aspirin-triggered resolvin D1 controls herpes simplex virus-induced corneal immunopathology. J Leukoc Biol 102:1159-1171
Varanasi, Siva Karthik; Reddy, Pradeep B J; Bhela, Siddheshvar et al. (2017) Azacytidine Treatment Inhibits the Progression of Herpes Stromal Keratitis by Enhancing Regulatory T Cell Function. J Virol 91:
Varanasi, Siva Karthik; Donohoe, Dallas; Jaggi, Ujjaldeep et al. (2017) Manipulating Glucose Metabolism during Different Stages of Viral Pathogenesis Can Have either Detrimental or Beneficial Effects. J Immunol 199:1748-1761
Bhela, Siddheshvar; Varanasi, Siva Karthik; Jaggi, Ujjaldeep et al. (2017) The Plasticity and Stability of Regulatory T Cells during Viral-Induced Inflammatory Lesions. J Immunol 199:1342-1352
Gimenez, Fernanda; Bhela, Siddheshvar; Dogra, Pranay et al. (2016) The inflammasome NLRP3 plays a protective role against a viral immunopathological lesion. J Leukoc Biol 99:647-57
Rajasagi, Naveen K; Rouse, Barry T (2016) IL-2 complex treatment amplifies CD8+ T cell mediated immunity following herpes simplex virus-1 infection. Microbes Infect 18:735-746

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