Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
7R01EY005690-11
Application #
3261077
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1990-08-15
Project End
1992-06-30
Budget Start
1990-08-15
Budget End
1991-06-30
Support Year
11
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Omura, Takao; Omura, Kumiko; Tedeschi, Andrea et al. (2015) Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron 86:1215-27
Kurimoto, Takuji; Yin, Yuqin; Habboub, Ghaith et al. (2013) Neutrophils express oncomodulin and promote optic nerve regeneration. J Neurosci 33:14816-24
Roh, Miin; Zhang, Yan; Murakami, Yusuke et al. (2012) Etanercept, a widely used inhibitor of tumor necrosis factor-? (TNF-?), prevents retinal ganglion cell loss in a rat model of glaucoma. PLoS One 7:e40065
de Lima, Silmara; Koriyama, Yoshiki; Kurimoto, Takuji et al. (2012) Full-length axon regeneration in the adult mouse optic nerve and partial recovery of simple visual behaviors. Proc Natl Acad Sci U S A 109:9149-54
Benowitz, Larry I; Popovich, Phillip G (2011) Inflammation and axon regeneration. Curr Opin Neurol 24:577-83
Kurimoto, Takuji; Yin, Yuqin; Omura, Kumiko et al. (2010) Long-distance axon regeneration in the mature optic nerve: contributions of oncomodulin, cAMP, and pten gene deletion. J Neurosci 30:15654-63
Benowitz, Larry I; Yin, Yuqin (2010) Optic nerve regeneration. Arch Ophthalmol 128:1059-64
Yin, Yuqin; Cui, Qi; Gilbert, Hui-Ya et al. (2009) Oncomodulin links inflammation to optic nerve regeneration. Proc Natl Acad Sci U S A 106:19587-92
Lorber, Barbara; Howe, Mariko L; Benowitz, Larry I et al. (2009) Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways. Nat Neurosci 12:1407-14
Cui, Q; Yin, Y; Benowitz, L I (2009) The role of macrophages in optic nerve regeneration. Neuroscience 158:1039-48

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