Enhancement of video images should enable the visual impaired greater access to TV. and other video sources. In previous years, contrast enhancement based on a band-pass filtering approach was developed and tested. Results were encouraging, showing improved performance in face recognition and in obtaining details from motion videos. Addition improvement will be gained by addressing other aspects of spatial vision beyond the loss of contrast sensitivity. We will study, in patients with central scotomas, the addition of wide-band feature markers improve the performance in localization, and in phase (shape) discrimination tasks, as suggested by studies carried out with normally sighted subjects. Using the results of these studies, we developed a novel extension of the previously used enhancement method, a wide-band enhancement that should have many advantages. The new method as a cartoon-like bar outlines (bipolar light and darkness) and increase the contrast of edge features to facilitate localization and discrimination. We will determine the optical parameters for such enhancement for patients with central scotomas, implement a software based approach to generate enhanced motion video segments and use such segments to measure the preference of visually impaired persons for the enhanced versions. We will continue to develop our visual model, and to use it in the development, evaluation and optimization of image enhancement for the visually impaired. The basic aspect of the study will examine changes in adaptation that occur in the peripheral visual processing with long term central visual loss. We will study performance differences on the number of visual tasks between patients with long term bilateral scotomas and with unilateral scotomas. The study of patients with monocular scotomas will provide better measure of the capability of the peripheral retina. The differences between monocular and bilateral scotomas patients performance will improve our understanding of adaptation to the force used of peripheral retina or form vision. Studies of long term facilitation low vision patients will be used in search for a measure of visual function that will explain and quantify deficit in peripheral retinal such as contour integration. The basic studies results will guide further fine tuning and optimization of the enhancement technique.

National Institute of Health (NIH)
National Eye Institute (NEI)
Research Project (R01)
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Special Emphasis Panel (ZRG1-VISB (02))
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Oberdorfer, Michael
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Schepens Eye Research Institute
United States
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Vera-Diaz, Fuensanta A; Woods, Russell L; Peli, Eli (2017) Blur Adaptation to Central Retinal Disease. Invest Ophthalmol Vis Sci 58:3646-3655
Jung, Jae-Hyun; Pu, Tian; Peli, Eli (2016) Comparing object recognition from binary and bipolar edge images for visual prostheses. J Electron Imaging 25:
Jung, Jae-Hyun; Pu, Tian; Peli, Eli (2016) Comparing object recognition from binary and bipolar edge features. IS&T Int Symp Electron Imaging 2016:
Jung, Jae-Hyun; Aloni, Doron; Yitzhaky, Yitzhak et al. (2015) Active confocal imaging for visual prostheses. Vision Res 111:182-96
Radhakrishnan, Aiswaryah; Sawides, Lucie; Dorronsoro, Carlos et al. (2015) Single neural code for blur in subjects with different interocular optical blur orientation. J Vis 15:15
Haun, Andrew M; Peli, Eli (2015) Similar Sensitivity to Ladder Contours in Macular Degeneration Patients and Controls. PLoS One 10:e0128119
García-Pérez, Miguel A; Peli, Eli (2015) Aniseikonia Tests: The Role of Viewing Mode, Response Bias, and Size-Color Illusions. Transl Vis Sci Technol 4:9
Hwang, Alex D; Peli, Eli (2014) An augmented-reality edge enhancement application for Google Glass. Optom Vis Sci 91:1021-30
Haun, Andrew M; Peli, Eli (2014) Binocular rivalry with peripheral prisms used for hemianopia rehabilitation. Ophthalmic Physiol Opt 34:573-9
Dilks, Daniel D; Julian, Joshua B; Peli, Eli et al. (2014) Reorganization of visual processing in age-related macular degeneration depends on foveal loss. Optom Vis Sci 91:e199-206

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