The overall purpose of this continuing project is to understand the contributions of mechanisms at various levels of visual processing to color vision, with particular interest in higher level mechanisms, that is, those beyond the conventional second stage mechanisms. A central aspect of the work is the coordination of investigations in psychophysics done at New York University and electrophysiology done in a continuing collaboration with Prof. Peter Lennie at the University of Rochester. The main aims are: 1. To study color discrimination under conditions of constant adaptation over an extended range of chromaticities and luminances and in detail over theoretically important regions. 2. To further test the hypothesis that photon noise plays a role in determining the detectability of increments on backgrounds. 3. To advance knowledge about the relative number and distribution of cone receptors by measuring the color appearance of small monochromatic stimuli imaged with the aid of adaptive optics. 4. To determine whether there are privileged directions in color space along which observers more readily abstract color appearance. 5. To continue collaborative electrophysiological experiments relating to significant issues in color vision. 6. To attempt to resolve the conflict between estimates of the relative sensitivity of the L and M cones based on two lines of evidence.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY006638-12A1
Application #
2614260
Study Section
Visual Sciences B Study Section (VISB)
Project Start
1986-09-01
Project End
2002-02-28
Budget Start
1998-03-01
Budget End
1999-02-28
Support Year
12
Fiscal Year
1998
Total Cost
Indirect Cost
Name
New York University
Department
Neurology
Type
Schools of Arts and Sciences
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012
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Krauskopf, J; Gegenfurtner, K (1992) Color discrimination and adaptation. Vision Res 32:2165-75
Krauskopf, J; Farell, B (1991) Vernier acuity: effects of chromatic content, blur and contrast. Vision Res 31:735-49
Lennie, P; Krauskopf, J; Sclar, G (1990) Chromatic mechanisms in striate cortex of macaque. J Neurosci 10:649-69
Chu, P; Grunwald, G B (1990) Generation and characterization of monoclonal antibodies specific for the retinal pigment epithelium. Invest Ophthalmol Vis Sci 31:856-62