Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
1R01EY007641-01
Application #
3264689
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1988-08-01
Project End
1993-07-31
Budget Start
1988-08-01
Budget End
1989-07-31
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Neelam, Sudha; Mellon, Jessamee; Wilkerson, Amber et al. (2018) Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation. Invest Ophthalmol Vis Sci 59:4738-4747
Mo, Juan; Neelam, Sudha; Mellon, Jessamee et al. (2017) Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens. Invest Ophthalmol Vis Sci 58:137-148
Ligocki, Ann J; Niederkorn, Jerry Y (2015) Advances on Non-CD4 + Foxp3+ T Regulatory Cells: CD8+, Type 1, and Double Negative T Regulatory Cells in Organ Transplantation. Transplantation 99:1553-9
Paunicka, K J; Mellon, J; Robertson, D et al. (2015) Severing corneal nerves in one eye induces sympathetic loss of immune privilege and promotes rejection of future corneal allografts placed in either eye. Am J Transplant 15:1490-501
Niederkorn, Jerry Y (2015) Immunology of Corneal Allografts: Insights from Animal Models. J Clin Exp Ophthalmol 6:
Cunnusamy, K; Niederkorn, J Y (2013) IFN-? blocks CD4+CD25+ Tregs and abolishes immune privilege of minor histocompatibility mismatched corneal allografts. Am J Transplant 13:3076-84
Niederkorn, Jerry Y (2013) Corneal transplantation and immune privilege. Int Rev Immunol 32:57-67
Reyes, N J; Chen, P W; Niederkorn, J Y (2013) Allergic conjunctivitis renders CD4(+) T cells resistant to t regulatory cells and exacerbates corneal allograft rejection. Am J Transplant 13:1181-92
Reyes, Nancy J; Mayhew, Elizabeth; Chen, Peter W et al. (2011) ?? T cells are required for maximal expression of allergic conjunctivitis. Invest Ophthalmol Vis Sci 52:2211-6
Cunnusamy, Khrishen; Chen, Peter W; Niederkorn, Jerry Y (2011) IL-17A-dependent CD4+CD25+ regulatory T cells promote immune privilege of corneal allografts. J Immunol 186:6737-45

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