Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY007892-08
Application #
2161756
Study Section
Special Emphasis Panel (ZRG1-VISB (01))
Project Start
1989-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Talla, Venu; Koilkonda, Rajeshwari; Porciatti, Vittorio et al. (2015) Complex I subunit gene therapy with NDUFA6 ameliorates neurodegeneration in EAE. Invest Ophthalmol Vis Sci 56:1129-40
Talla, Venu; Porciatti, Vittorio; Chiodo, Vince et al. (2014) Gene therapy with mitochondrial heat shock protein 70 suppresses visual loss and optic atrophy in experimental autoimmune encephalomyelitis. Invest Ophthalmol Vis Sci 55:5214-26
Yu, Bo; Xu, Pei; Zhao, Zhenyang et al. (2014) Subcellular distribution and activity of mechanistic target of rapamycin in aged retinal pigment epithelium. Invest Ophthalmol Vis Sci 55:8638-50
Talla, Venu; Yu, Hong; Chou, Tsung-Han et al. (2013) NADH-dehydrogenase type-2 suppresses irreversible visual loss and neurodegeneration in the EAE animal model of MS. Mol Ther 21:1876-88
Brantley Jr, Milam A; Osborn, Melissa P; Sanders, Barton J et al. (2012) Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration. Am J Ophthalmol 153:460-467.e1
Brantley Jr, Milam A; Osborn, Melissa P; Sanders, Barton J et al. (2012) The short-term effects of antioxidant and zinc supplements on oxidative stress biomarker levels in plasma: a pilot investigation. Am J Ophthalmol 153:1104-9.e2
Zhao, Zhenyang; Chen, Yan; Wang, Jian et al. (2011) Age-related retinopathy in NRF2-deficient mice. PLoS One 6:e19456
Rezaei, Kasra A; Toma, Hassanain S; Cai, Jiyang et al. (2011) Reduced choroidal neovascular membrane formation in cyclooxygenase-2 null mice. Invest Ophthalmol Vis Sci 52:701-7
Kuchtey, John; Rezaei, Kasra A; Jaru-Ampornpan, Pimkwan et al. (2010) Multiplex cytokine analysis reveals elevated concentration of interleukin-8 in glaucomatous aqueous humor. Invest Ophthalmol Vis Sci 51:6441-7
Chen, Yan; Wang, Jian; Cai, Jiyang et al. (2010) Altered mTOR signaling in senescent retinal pigment epithelium. Invest Ophthalmol Vis Sci 51:5314-9

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