Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY008061-09
Application #
2161963
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1990-02-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Jastrzebska, Beata; Chen, Yuanyuan; Orban, Tivadar et al. (2015) Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface. J Biol Chem 290:25728-44
Hofmann, Lukas; Palczewski, Krzysztof (2015) The G protein-coupled receptor rhodopsin: a historical perspective. Methods Mol Biol 1271:3-18
Baker, Bo Y; Gulati, Sahil; Shi, Wuxian et al. (2015) Crystallization of proteins from crude bovine rod outer segments. Methods Enzymol 557:439-58
Palczewska, Grazyna; Salom, David (2015) Imaging of rhodopsin crystals with two-photon microscopy. Methods Mol Biol 1271:55-64
Chen, Yuanyuan; Jastrzebska, Beata; Cao, Pengxiu et al. (2014) Inherent instability of the retinitis pigmentosa P23H mutant opsin. J Biol Chem 289:9288-303
Mustafi, Debarshi; Kikano, Sandra; Palczewski, Krzysztof (2014) Serial block face-scanning electron microscopy: a method to study retinal degenerative phenotypes. Curr Protoc Mouse Biol 4:197-204
Tu, Xiongying; Palczewski, Krzysztof (2014) The macular degeneration-linked C1QTNF5 (S163) mutation causes higher-order structural rearrangements. J Struct Biol 186:86-94
Baker, Bo Y; Shi, Wuxian; Wang, Benlian et al. (2014) High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules. Protein Sci 23:1629-39
Orban, Tivadar; Jastrzebska, Beata; Palczewski, Krzysztof (2014) Structural approaches to understanding retinal proteins needed for vision. Curr Opin Cell Biol 27:32-43
Chen, Yuanyuan; Tang, Hong; Seibel, William et al. (2014) Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase. Mol Pharmacol 86:231-42

Showing the most recent 10 out of 126 publications