Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY008379-07
Application #
2162218
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1993-07-01
Project End
1995-06-30
Budget Start
1995-01-01
Budget End
1995-06-30
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Boston University
Department
Dermatology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Bhol, K C; Colon, J E; Ahmed, A R (2003) Autoantibody in mucous membrane pemphigoid binds to an intracellular epitope on human beta4 integrin and causes basement membrane zone separation in oral mucosa in an organ culture model. J Invest Dermatol 120:701-2
Razzaque, Mohammed S; Ahmed, Babar S; Foster, C Stephen et al. (2003) Effects of IL-4 on conjunctival fibroblasts: possible role in ocular cicatricial pemphigoid. Invest Ophthalmol Vis Sci 44:3417-23
Razzaque, Mohammed S; Foster, C Stephen; Ahmed, A Razzaque (2003) Role of connective tissue growth factor in the pathogenesis of conjunctival scarring in ocular cicatricial pemphigoid. Invest Ophthalmol Vis Sci 44:1998-2003
Razzaque, Mohammed S; Foster, C Stephen; Ahmed, A Razzaque (2002) Role of enhanced expression of m-CSF in conjunctiva affected by cicatricial pemphigoid. Invest Ophthalmol Vis Sci 43:2977-83
Colon, J E; Bhol, K C; Razzaque, M S et al. (2001) In vitro organ culture model for mucous membrane pemphigoid. Clin Immunol 98:229-34
Kumari, S; Bhol, K C; Simmons, R K et al. (2001) Identification of ocular cicatricial pemphigoid antibody binding site(s) in human beta4 integrin. Invest Ophthalmol Vis Sci 42:379-85
Kumari, S; Bhol, K C; Rehman, F et al. (2001) Interleukin 1 components in cicatricial pemphigoid. Role in intravenous immunoglobulin therapy. Cytokine 14:218-24
Engineer, L; Bhol, K; Kumari, S et al. (2001) Bullous pemphigoid: interaction of interleukin 5, anti-basement membrane zone antibodies and eosinophils. A preliminary observation. . Cytokine 13:32-38
Bhol, K C; Goss, L; Kumari, S et al. (2001) Autoantibodies to human alpha6 integrin in patients with oral pemphigoid. J Dent Res 80:1711-5
Bhol, K C; Dans, M J; Simmons, R K et al. (2000) The autoantibodies to alpha 6 beta 4 integrin of patients affected by ocular cicatricial pemphigoid recognize predominantly epitopes within the large cytoplasmic domain of human beta 4. J Immunol 165:2824-9

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