|
Kirk, Sarah R; Andrade, Adriana L; Melich, Kenneth et al. (2011) Halogen substituents on the aromatic moiety of the tetracaine scaffold improve potency of cyclic nucleotide-gated channel block. Bioorg Med Chem Lett 21:6417-9
|
|
Andrade, Adriana L; Melich, Kenneth; Whatley, G Gregory et al. (2011) Cyclic nucleotide-gated channel block by hydrolysis-resistant tetracaine derivatives. J Med Chem 54:4904-12
|
|
Strassmaier, Timothy; Kirk, Sarah R; Banerji, Tapasree et al. (2008) Block of cyclic nucleotide-gated channels by tetracaine derivatives: role of apolar interactions at two distinct locations. Bioorg Med Chem Lett 18:645-9
|
|
Strassmaier, Timothy; Karpen, Jeffrey W (2007) Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels. J Med Chem 50:4186-94
|
|
Rich, Thomas C; Xin, Wenkuan; Mehats, Celine et al. (2007) Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells. Am J Physiol Cell Physiol 292:C319-31
|
|
Brady, James D; Rich, Elizabeth D; Martens, Jeffrey R et al. (2006) Interplay between PIP3 and calmodulin regulation of olfactory cyclic nucleotide-gated channels. Proc Natl Acad Sci U S A 103:15635-40
|
|
Karpen, Jeffrey W; Rich, Thomas C (2004) Resolution of cAMP signals in three-dimensional microdomains using novel, real-time sensors. Proc West Pharmacol Soc 47:1-5
|
|
Ghatpande, Ambarish S; Uma, Ramalinga; Karpen, Jeffrey W (2003) A multiply charged tetracaine derivative blocks cyclic nucleotide-gated channels at subnanomolar concentrations. Biochemistry 42:265-70
|
|
Rich, Thomas C; Karpen, Jeffrey W (2002) Review article: cyclic AMP sensors in living cells: what signals can they actually measure? Ann Biomed Eng 30:1088-99
|
|
Rich, T C; Fagan, K A; Tse, T E et al. (2001) A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell. Proc Natl Acad Sci U S A 98:13049-54
|
Showing the most recent 10 out of 22 publications
