Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009532-04
Application #
2163120
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1993-01-01
Project End
1997-06-30
Budget Start
1996-01-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Louisville
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
City
Louisville
State
KY
Country
United States
Zip Code
40292
Mandal, Amritlal; Shahidullah, Mohammad; Delamere, Nicholas A (2018) TRPV1-dependent ERK1/2 activation in porcine lens epithelium. Exp Eye Res 172:128-136
Delamere, Nicholas A; Mandal, Amritlal; Shahidullah, Mohammad (2016) The Significance of TRPV4 Channels and Hemichannels in the Lens and Ciliary Epithelium. J Ocul Pharmacol Ther 32:504-508
Gao, Junyuan; Sun, Xiurong; White, Thomas W et al. (2015) Feedback Regulation of Intracellular Hydrostatic Pressure in Surface Cells of the Lens. Biophys J 109:1830-9
Shahidullah, M; Mandal, A; Delamere, N A (2015) Damage to lens fiber cells causes TRPV4-dependent Src family kinase activation in the epithelium. Exp Eye Res 140:85-93
Mandal, Amritlal; Shahidullah, Mohammad; Delamere, Nicholas A (2015) Calcium entry via connexin hemichannels in lens epithelium. Exp Eye Res 132:52-8
Beckel, Jonathan M; Argall, Arthur J; Lim, Jason C et al. (2014) Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvement in chronic strain. Glia 62:1486-501
Sanderson, Julie; Dartt, Darlene A; Trinkaus-Randall, Vickery et al. (2014) Purines in the eye: recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Müller cells, lens, trabecular meshwork, cornea and lacrimal gland. Exp Eye Res 127:270-9
Shahidullah, Mohammad; Mandal, Amritlal; Delamere, Nicholas A (2012) TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. Am J Physiol Cell Physiol 302:C1751-61
Shahidullah, M; Mandal, A; Beimgraben, C et al. (2012) Hyposmotic stress causes ATP release and stimulates Na,K-ATPase activity in porcine lens. J Cell Physiol 227:1428-37
Mandal, A; Shahidullah, M; Beimgraben, C et al. (2011) The effect of endothelin-1 on Src-family tyrosine kinases and Na,K-ATPase activity in porcine lens epithelium. J Cell Physiol 226:2555-61

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