Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
3R01EY010564-02S1
Application #
2164522
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1994-09-30
Project End
1999-09-29
Budget Start
1995-09-30
Budget End
1996-09-29
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Iowa
Department
Pediatrics
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Lu, Wennan; Hu, HuiLing; Sévigny, Jean et al. (2015) Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye. Invest Ophthalmol Vis Sci 56:3075-83
Zode, Gulab S; Sharma, Arti B; Lin, Xiaolei et al. (2014) Ocular-specific ER stress reduction rescues glaucoma in murine glucocorticoid-induced glaucoma. J Clin Invest 124:1956-65
Beckel, Jonathan M; Argall, Arthur J; Lim, Jason C et al. (2014) Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvement in chronic strain. Glia 62:1486-501
Scheetz, Todd E; Fingert, John H; Wang, Kai et al. (2013) A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. PLoS One 8:e58657
Zode, Gulab S; Bugge, Kevin E; Mohan, Kabhilan et al. (2012) Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma. Invest Ophthalmol Vis Sci 53:1557-65
Davis, Lea K; Meyer, Kacie J; Schindler, Emily I et al. (2011) Copy number variations and primary open-angle glaucoma. Invest Ophthalmol Vis Sci 52:7122-33
Zode, Gulab S; Kuehn, Markus H; Nishimura, Darryl Y et al. (2011) Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma. J Clin Invest 121:3542-53
Meyer, Kacie J; Davis, Lea K; Schindler, Emily I et al. (2011) Genome-wide analysis of copy number variants in age-related macular degeneration. Hum Genet 129:91-100
Fingert, John H; Robin, Alan L; Stone, Jennifer L et al. (2011) Copy number variations on chromosome 12q14 in patients with normal tension glaucoma. Hum Mol Genet 20:2482-94
Walters, Jesse D; Bair, Thomas B; Braun, Terry A et al. (2009) Multi-granularity Parallel Computing in a Genome-Scale Molecular Evolution Application. J Supercomput 5698:49-59

Showing the most recent 10 out of 54 publications