Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY011123-02
Application #
2165400
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1995-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Florida
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Ku, Cristy A; Chiodo, Vince A; Boye, Sanford L et al. (2015) Viral-mediated vision rescue of a novel AIPL1 cone-rod dystrophy model. Hum Mol Genet 24:670-84
Dai, Xufeng; Han, Juanjuan; Qi, Yan et al. (2014) AAV-mediated lysophosphatidylcholine acyltransferase 1 (Lpcat1) gene replacement therapy rescues retinal degeneration in rd11 mice. Invest Ophthalmol Vis Sci 55:1724-34
Zhu, Yongling; Xu, Jian; Hauswirth, William W et al. (2014) Genetically targeted binary labeling of retinal neurons. J Neurosci 34:7845-61
Boye, Sanford L; Peshenko, Igor V; Huang, Wei Chieh et al. (2013) AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of Leber congenital amaurosis. Hum Gene Ther 24:189-202
Komáromy, András M; Rowlan, Jessica S; Corr, Amanda T Parton et al. (2013) Transient photoreceptor deconstruction by CNTF enhances rAAV-mediated cone functional rescue in late stage CNGB3-achromatopsia. Mol Ther 21:1131-41
Mao, Haoyu; Gorbatyuk, Marina S; Rossmiller, Brian et al. (2012) Long-term rescue of retinal structure and function by rhodopsin RNA replacement with a single adeno-associated viral vector in P23H RHO transgenic mice. Hum Gene Ther 23:356-66
Boye, Shannon E; Alexander, John J; Boye, Sanford L et al. (2012) The human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina. Hum Gene Ther 23:1101-15
Deng, Wen-Tao; Dinculescu, Astra; Li, Qiuhong et al. (2012) Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats. Invest Ophthalmol Vis Sci 53:1895-904
Verma, Amrisha; Shan, Zhiying; Lei, Bo et al. (2012) ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Mol Ther 20:28-36
Dinculescu, Astra; Estreicher, Jackie; Zenteno, Juan C et al. (2012) Gene therapy for retinitis pigmentosa caused by MFRP mutations: human phenotype and preliminary proof of concept. Hum Gene Ther 23:367-76

Showing the most recent 10 out of 91 publications