Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM020818-18
Application #
3270172
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1977-04-01
Project End
1992-06-30
Budget Start
1992-01-01
Budget End
1992-06-30
Support Year
18
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Ziemniak, Marcin; Mugridge, Jeffrey S; Kowalska, Joanna et al. (2016) Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex. RNA 22:518-29
Korneeva, Nadejda L; Song, Anren; Gram, Hermann et al. (2016) Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin. J Biol Chem 291:3455-67
Fan, Ruping; Schrott, Lisa M; Snelling, Stephen et al. (2015) Chronic oxycodone induces integrated stress response in rat brain. BMC Neurosci 16:58
Kowalska, Joanna; Wypijewska del Nogal, Anna; Darzynkiewicz, Zbigniew M et al. (2014) Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes. Nucleic Acids Res 42:10245-64
Grudzien-Nogalska, Ewa; Reed, Brent C; Rhoads, Robert E (2014) CPEB1 promotes differentiation and suppresses EMT in mammary epithelial cells. J Cell Sci 127:2326-38
Ziemniak, Marcin; Szabelski, Mariusz; Lukaszewicz, Maciej et al. (2013) Synthesis and evaluation of fluorescent cap analogues for mRNA labelling. RSC Adv 3:
Su, Wei; Slepenkov, Sergey V; Slevin, Michael K et al. (2013) mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end. RNA 19:1-16
Su, Wei; Slepenkov, Sergey; Grudzien-Nogalska, Ewa et al. (2011) Translation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NH. RNA 17:978-88
Chiluiza, David; Bargo, Sharon; Callahan, Robert et al. (2011) Expression of truncated eukaryotic initiation factor 3e (eIF3e) resulting from integration of mouse mammary tumor virus (MMTV) causes a shift from cap-dependent to cap-independent translation. J Biol Chem 286:31288-96
Senkovich, Olga A; Yin, Jun; Ekshyyan, Viktoriya et al. (2011) Helicobacter pylori AlpA and AlpB bind host laminin and influence gastric inflammation in gerbils. Infect Immun 79:3106-16

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