Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM021313-22
Application #
2173693
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1974-10-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Mears, M L; Hutchison 3rd, C A (2001) The evolution of modern lineages of mouse L1 elements. J Mol Evol 52:51-62
Montague, M G; Hutchison 3rd, C A (2000) Gene content phylogeny of herpesviruses. Proc Natl Acad Sci U S A 97:5334-9
Wrobel, J A; Conrad, M J; Bloedon, E et al. (2000) Analysis of HIV type 1 reverse transcriptase: comparing sequences of viral isolates with mutational data. AIDS Res Hum Retroviruses 16:2049-54
Lahr, S J; Broadwater, A; Carter Jr, C W et al. (1999) Patterned library analysis: a method for the quantitative assessment of hypotheses concerning the determinants of protein structure. Proc Natl Acad Sci U S A 96:14860-5
Wrobel, J A; Chao, S F; Conrad, M J et al. (1998) A genetic approach for identifying critical residues in the fingers and palm subdomains of HIV-1 reverse transcriptase. Proc Natl Acad Sci U S A 95:638-45
Tollefsbol, T O; Hutchison 3rd, C A (1998) Analysis in Escherichia coli of the effects of in vivo CpG methylation catalyzed by the cloned murine maintenance methyltransferase. Biochem Biophys Res Commun 245:670-8
Tollefsbol, T O; Hutchison 3rd, C A (1997) Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase. J Mol Biol 269:494-504
Davies, C J; Hutchison 3rd, C A (1995) Insertion site specificity of the transposon Tn3. Nucleic Acids Res 23:507-14
Peterson, S N; Bailey, C C; Jensen, J S et al. (1995) Characterization of repetitive DNA in the Mycoplasma genitalium genome: possible role in the generation of antigenic variation. Proc Natl Acad Sci U S A 92:11829-33
Tollefsbol, T O; Hutchison 3rd, C A (1995) Mammalian DNA (cytosine-5-)-methyltransferase expressed in Escherichia coli, purified and characterized. J Biol Chem 270:18543-50

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