Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM021447-21
Application #
2173733
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1977-12-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Albany Medical College
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Albany
State
NY
Country
United States
Zip Code
12208
Rotundo, Robert F; Curtis, Theresa M; Shah, Melissa D et al. (2002) TNF-alpha disruption of lung endothelial integrity: reduced integrin mediated adhesion to fibronectin. Am J Physiol Lung Cell Mol Physiol 282:L316-29
Gao, Baochong; Saba, Thomas M; Tsan, Min-Fu (2002) Role of alpha(v)beta(3)-integrin in TNF-alpha-induced endothelial cell migration. Am J Physiol Cell Physiol 283:C1196-205
Chen, R; Gao, B; Huang, C et al. (2000) Transglutaminase-mediated fibronectin multimerization in lung endothelial matrix in response to TNF-alpha. Am J Physiol Lung Cell Mol Physiol 279:L161-74
Gao, B; Curtis, T M; Blumenstock, F A et al. (2000) Increased recycling of (alpha)5(beta)1 integrins by lung endothelial cells in response to tumor necrosis factor. J Cell Sci 113 Pt 2:247-57
Resnikoff, M; Brien, T; Vincent, P A et al. (1999) Lung matrix incorporation of plasma fibronectin reduces vascular permeability in postsurgical bacteremia. Am J Physiol 277:L749-59
Rotundo, R F; Vincent, P A; McKeown-Longo, P J et al. (1999) Hepatic fibronectin matrix turnover in rats: involvement of the asialoglycoprotein receptor. Am J Physiol 277:G1189-99
Curtis, T M; Rotundo, R F; Vincent, P A et al. (1998) TNF-alpha-induced matrix Fn disruption and decreased endothelial integrity are independent of Fn proteolysis. Am J Physiol 275:L126-38
Brien, T P; Reddy, P P; Vincent, P A et al. (1998) Lung matrix deposition of normal and alkylated plasma fibronectin: response to postsurgical sepsis. Am J Physiol 274:L432-43
Rotundo, R F; Rebres, R A; Mckeown-Longo, P J et al. (1998) Circulating cellular fibronectin may be a natural ligand for the hepatic asialoglycoprotein receptor: possible pathway for fibronectin deposition and turnover in the rat liver. Hepatology 28:475-85
Rebres, R A; Cho, E; Rotundo, R F et al. (1996) Reduced in vivo plasma fibronectin content of lung matrix during postoperative sepsis. Am J Physiol 271:L409-18

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