Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM022079-20
Application #
2173859
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1978-05-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nebraska Lincoln
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
555456995
City
Lincoln
State
NE
Country
United States
Zip Code
68588
Datta, B; Datta, R (1999) Induction of apoptosis due to lowering the level of eukaryotic initiation factor 2-associated protein, p67, from mammalian cells by antisense approach. Exp Cell Res 246:376-83
Datta, B; Datta, R; Mukherjee, S et al. (1999) Increased phosphorylation of eukaryotic initiation factor 2alpha at the G2/M boundary in human osteosarcoma cells correlates with deglycosylation of p67 and a decreased rate of protein synthesis. Exp Cell Res 250:223-30
Chatterjee, M; Chatterjee, N; Datta, R et al. (1998) Expression and activity of p67 are induced during heat shock. Biochem Biophys Res Commun 249:113-7
Zou, C; Zhang, Z; Wu, S et al. (1998) Molecular cloning and characterization of a rabbit eIF2C protein. Gene 211:187-94
Saha, D; Wu, S; Bose, A et al. (1997) Viral infection. II. Hemin induces overexpression of p67 as it partially prevents appearance of an active p67-deglycosylase in baculovirus-infected insect cells. Arch Biochem Biophys 342:373-82
Gupta, S; Wu, S; Chatterjee, N et al. (1995) Regulation of an eukaryotic initiation factor-2 (eIF-2) associated 67 kDa glycoprotein (p67) and its requirement in protein synthesis. Gene Expr 5:113-22
Chakraborty, A; Saha, D; Bose, A et al. (1994) Mechanism of action of an eukaryotic initiation factor-2 (eIF-2) associated 67 kDa glycoprotein (p67) and an eIF-2 kinase (dsI). Indian J Biochem Biophys 31:236-42
Parkhurst, K M; Hileman, R E; Saha, D et al. (1994) Thermodynamic characterization of the cooperativity of 40S complex formation during the initiation of eukaryotic protein synthesis. Biochemistry 33:15168-77
Chakraborty, A; Saha, D; Bose, A et al. (1994) Regulation of eIF-2 alpha-subunit phosphorylation in reticulocyte lysate. Biochemistry 33:6700-6
Hileman, R E; Parkhurst, K M; Gupta, N K et al. (1994) Synthesis and characterization of conjugates formed between periodate-oxidized ribonucleotides and amine-containing fluorophores. Bioconjug Chem 5:436-44

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