Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM022135-22
Application #
2173879
Study Section
Biochemistry Study Section (BIO)
Project Start
1978-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Davis
Department
Biochemistry
Type
Schools of Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Henderson, Allen; Hershey, John W (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108:6415-9
Shi, Jiaqi; Hershey, John W B; Nelson, Mark A (2009) Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis. FEBS Lett 583:971-7
Zhang, Lili; Smit-McBride, Zeljka; Pan, Xiaoyu et al. (2008) An oncogenic role for the phosphorylated h-subunit of human translation initiation factor eIF3. J Biol Chem 283:24047-60
Komarova, Anastassia V; Real, Eleonore; Borman, Andrew M et al. (2007) Rabies virus matrix protein interplay with eIF3, new insights into rabies virus pathogenesis. Nucleic Acids Res 35:1522-32
Shi, J; Kahle, A; Hershey, J W B et al. (2006) Decreased expression of eukaryotic initiation factor 3f deregulates translation and apoptosis in tumor cells. Oncogene 25:4923-36
Shahbazian, David; Roux, Philippe P; Mieulet, Virginie et al. (2006) The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. EMBO J 25:2781-91
Miyamoto, Suzanne; Patel, Purvi; Hershey, John W B (2005) Changes in ribosomal binding activity of eIF3 correlate with increased translation rates during activation of T lymphocytes. J Biol Chem 280:28251-64
Fraser, Christopher S; Hershey, John W B (2005) Movement in ribosome translocation. J Biol 4:8
Fraser, Christopher S; Lee, Jennifer Y; Mayeur, Greg L et al. (2004) The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro. J Biol Chem 279:8946-56
Raught, Brian; Peiretti, Franck; Gingras, Anne-Claude et al. (2004) Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. EMBO J 23:1761-9

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