The general objective of the research to be undertaken is to provide applicable and informative statistical methods for the analysis of experiments and the evaluation of therapeutic and other trials in the Biomedical area. The principal focus will be on predictive or observabilistic inference and decision making. This will entail obtaining algorithms for calculating the probability distribution of particular functions of future observables useful in sampling curtailment developing methods for assessing whether certain standard statistical models are robust to particular perturbations, testing for discordancy of possibly aberrant observations, providing optimal rules for administering diagnostic screening programs for a condition or diseast, devising optimal statistical methods for the regulation or control of responses associated with a disease, and comparing the effect on prediction of the estimation of hyperparameters in hierarchical models by maximum likelihood, method of moments and sample reuse techniques.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM025271-15
Application #
3272888
Study Section
Special Emphasis Panel (SSS (B6))
Project Start
1978-07-01
Project End
1994-06-30
Budget Start
1993-07-01
Budget End
1994-06-30
Support Year
15
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
Schools of Arts and Sciences
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455