Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM025638-17
Application #
2174495
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1978-07-01
Project End
1998-06-30
Budget Start
1995-07-01
Budget End
1998-06-30
Support Year
17
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Pedigo, Susan; Williams Jr, Robley C (2002) Concentration dependence of variability in growth rates of microtubules. Biophys J 83:1809-19
Shah, C; Xu, C Z; Vickers, J et al. (2001) Properties of microtubules assembled from mammalian tubulin synthesized in Escherichia coli. Biochemistry 40:4844-52
Detrich 3rd, H W; Parker, S K; Williams Jr, R C et al. (2000) Cold adaptation of microtubule assembly and dynamics. Structural interpretation of primary sequence changes present in the alpha- and beta-tubulins of Antarctic fishes. J Biol Chem 275:37038-47
Williams Jr, R C; Shah, C; Sackett, D (1999) Separation of tubulin isoforms by isoelectric focusing in immobilized pH gradient gels. Anal Biochem 275:265-7
Melki, R; Batelier, G; Soulie, S et al. (1997) Cytoplasmic chaperonin containing TCP-1: structural and functional characterization. Biochemistry 36:5817-26
Gamblin, T C; Nachmanoff, K; Halpain, S et al. (1996) Recombinant microtubule-associated protein 2c reduces the dynamic instability of individual microtubules. Biochemistry 35:12576-86
Dye, R B; Williams Jr, R C (1996) Assembly of microtubules from tubulin bearing the nonhydrolyzable guanosine triphosphate analogue GMPPCP [guanylyl 5'-(beta, gamma-methylenediphosphonate)]: variability of growth rates and the hydrolysis of GTP. Biochemistry 35:14331-9
Billger, M A; Bhattacharjee, G; Williams Jr, R C et al. (1996) Dynamic instability of microtubules assembled from microtubule-associated protein-free tubulin: neither variability of growth and shortening rates nor ""rescue"" requires microtubule-associated proteins. Biochemistry 35:13656-63
Kurz, J C; Williams Jr, R C (1995) Microtubule-associated proteins and the flexibility of microtubules. Biochemistry 34:13374-80
Harris, S J; Williams Jr, R C; Lee, J C (1995) Self-association of Escherichia coli DNA-dependent RNA polymerase core enzyme. Biochemistry 34:8752-62

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