Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM025671-09S1
Application #
3273221
Study Section
Biophysics and Biophysical Chemistry A Study Section (BBCA)
Project Start
1978-07-01
Project End
1989-06-30
Budget Start
1986-07-01
Budget End
1987-06-30
Support Year
9
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Arts and Sciences
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Duan, Y; Wilkosz, P; Crowley, M et al. (1997) Molecular dynamics simulation study of DNA dodecamer d(CGCGAATTCGCG) in solution: conformation and hydration. J Mol Biol 272:553-72
Duan, Y; Wilkosz, P; Rosenberg, J M (1996) Dynamic contributions to the DNA binding entropy of the EcoRI and EcoRV restriction endonucleases. J Mol Biol 264:546-55
Keyes, R S; Cao, Y Y; Bobst, E V et al. (1996) Spin-labeled nucleotide mobility in the boundary of the EcoRI endonuclease binding site. J Biomol Struct Dyn 14:163-72
Ding, Y; Duda, R L; Hendrix, R W et al. (1995) Complexes between chaperonin GroEL and the capsid protein of bacteriophage HK97. Biochemistry 34:14918-31
Kumar, S; Duan, Y; Kollman, P A et al. (1994) Molecular dynamics simulations suggest that the Eco RI kink is an example of molecular strain. J Biomol Struct Dyn 12:487-525
Kim, Y C; Grable, J C; Love, R et al. (1990) Refinement of Eco RI endonuclease crystal structure: a revised protein chain tracing. Science 249:1307-9
Hager, P W; Reich, N O; Day, J P et al. (1990) Probing the role of glutamic acid 144 in the EcoRI endonuclease using aspartic acid and glutamine replacements. J Biol Chem 265:21520-6
Needels, M C; Fried, S R; Love, R et al. (1989) Determinants of EcoRI endonuclease sequence discrimination. Proc Natl Acad Sci U S A 86:3579-83
Thomas, G A; Kubasek, W L; Peticolas, W L et al. (1989) Environmentally induced conformational changes in B-type DNA: comparison of the conformation of the oligonucleotide d(TCGCGAATTCGCG) in solution and in its crystalline complex with the restriction nuclease EcoRI. Biochemistry 28:2001-9
Greene, P J; Ballard, B T; Stephenson, F et al. (1988) Purification and characterization of the restriction endonuclease RsrI, an isoschizomer of EcoRI. Gene 68:43-51

Showing the most recent 10 out of 14 publications