Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM025953-18
Application #
2174572
Study Section
Biochemistry Study Section (BIO)
Project Start
1979-04-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Houston
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
800771594
City
Houston
State
TX
Country
United States
Zip Code
77204

  Publications

Ortego, Beatrice C; Whittenton, Jeremiah J; Li, Hui et al. (2007) In vivo translational inaccuracy in Escherichia coli: missense reporting using extremely low activity mutants of Vibrio harveyi luciferase. Biochemistry 46:13864-73
Lei, Benfang; Wang, He; Yu, Yimin et al. (2005) Redox potential and equilibria in the reductive half-reaction of Vibrio harveyi NADPH-FMN oxidoreductase. Biochemistry 44:261-7
Huang, Shouqin; Tu, Shiao-Chun (2005) Effects of iodide on the fluorescence and activity of the hydroperoxyflavin intermediate of Vibrio harveyi luciferase. Photochem Photobiol 81:425-30
Li, Chi-Hui; Tu, Shiao-Chun (2005) Active site hydrophobicity is critical to the bioluminescence activity of Vibrio harveyi luciferase. Biochemistry 44:12970-7
Li, Chi-Hui; Tu, Shiao-Chun (2005) Probing the functionalities of alphaGlu328 and alphaAla74 of Vibrio harveyi luciferase by site-directed mutagenesis and chemical rescue. Biochemistry 44:13866-73
Russell, Thomas R; Tu, Shiao-Chun (2004) Aminobacter aminovorans NADH:flavin oxidoreductase His140: a highly conserved residue critical for NADH binding and utilization. Biochemistry 43:12887-93
Russell, Thomas R; Demeler, Borries; Tu, Shiao-Chun (2004) Kinetic mechanism and quaternary structure of Aminobacter aminovorans NADH:flavin oxidoreductase: an unusual flavin reductase with bound flavin. Biochemistry 43:1580-90
Lei, Benfang; Ding, Qizhu; Tu, Shiao-Chun (2004) Identity of the emitter in the bacterial luciferase luminescence reaction: binding and fluorescence quantum yield studies of 5-decyl-4a-hydroxy-4a,5-dihydroriboflavin-5'-phosphate as a model. Biochemistry 43:15975-82
Low, John C; Tu, Shiao-Chun (2003) Energy transfer evidence for in vitro and in vivo complexes of Vibrio harveyi flavin reductase P and luciferase. Photochem Photobiol 77:446-52
Jeffers, Christopher E; Nichols, Jeffry C; Tu, Shiao-Chun (2003) Complex formation between Vibrio harveyi luciferase and monomeric NADPH:FMN oxidoreductase. Biochemistry 42:529-34

Showing the most recent 10 out of 51 publications