Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM026290-18A1
Application #
2174680
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1979-04-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Physiology
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Shi, Chenxu; Welsh, Patricia A; Sass-Kuhn, Suzanne et al. (2012) Characterization of transgenic mice with overexpression of spermidine synthase. Amino Acids 42:495-505
Green, Robert; Hanfrey, Colin C; Elliott, Katherine A et al. (2011) Independent evolutionary origins of functional polyamine biosynthetic enzyme fusions catalysing de novo diamine to triamine formation. Mol Microbiol 81:1109-24
Pegg, Anthony E; Casero Jr, Robert A (2011) Current status of the polyamine research field. Methods Mol Biol 720:3-35
Pegg, Anthony E; Wang, Xiaojing; Schwartz, Charles E et al. (2011) Spermine synthase activity affects the content of decarboxylated S-adenosylmethionine. Biochem J 433:139-44
Wang, Xiaojing; Pegg, Anthony E (2011) Use of (Gyro) Gy and spermine synthase transgenic mice to study functions of spermine. Methods Mol Biol 720:159-70
Pegg, Anthony E; Michael, Anthony J (2010) Spermine synthase. Cell Mol Life Sci 67:113-21
Pegg, Anthony E; Wang, Xiaojing (2009) Mouse models to investigate the function of spermine. Commun Integr Biol 2:271-4
Pegg, Anthony E (2009) Mammalian polyamine metabolism and function. IUBMB Life 61:880-94
Wang, Xiaojing; Levic, Snezana; Gratton, Michael Anne et al. (2009) Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine. J Biol Chem 284:930-7
Pegg, Anthony E (2009) S-Adenosylmethionine decarboxylase. Essays Biochem 46:25-45

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