Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM026698-17
Application #
2174767
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1979-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Schroeder, Avi; Goldberg, Michael S; Kastrup, Christian et al. (2012) Remotely activated protein-producing nanoparticles. Nano Lett 12:2685-9
Devitt, Gerard; Thomas, Mini; Klibanov, Alexander M et al. (2007) Optimized protocol for the large scale production of HIV pseudovirions by transient transfection of HEK293T cells with linear fully deacylated polyethylenimine. J Virol Methods 146:298-304
Thomas, Mini; Lu, James J; Zhang, Chengcheng et al. (2007) Identification of novel superior polycationic vectors for gene delivery by high-throughput synthesis and screening of a combinatorial library. Pharm Res 24:1564-71
Sharma, Vikas K; Klibanov, Alexander M (2007) Moisture-induced aggregation of lyophilized DNA and its prevention. Pharm Res 24:168-75
Berry, David; Lynn, David M; Berry, Eric et al. (2006) Heparin localization and fine structure regulate Burkitt's lymphoma growth. Biochem Biophys Res Commun 348:850-6
Thomas, Mini; Ge, Qing; Lu, James J et al. (2005) Cross-linked small polyethylenimines: while still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo. Pharm Res 22:373-80
Sharma, Vikas K; Thomas, Mini; Klibanov, Alexander M (2005) Mechanistic studies on aggregation of polyethylenimine-DNA complexes and its prevention. Biotechnol Bioeng 90:614-20
Colombo, Gaia; Padera, Robert; Langer, Robert et al. (2005) Prolonged duration local anesthesia with lipid-protein-sugar particles containing bupivacaine and dexamethasone. J Biomed Mater Res A 75:458-64
Haining, W Nicholas; Anderson, Daniel G; Little, Steven R et al. (2004) pH-triggered microparticles for peptide vaccination. J Immunol 173:2578-85
Klibanov, Alexander M; Schefiliti, Jennifer A (2004) On the relationship between conformation and stability in solid pharmaceutical protein formulations. Biotechnol Lett 26:1103-6

Showing the most recent 10 out of 90 publications