Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM027367-16S1
Application #
2395399
Study Section
Physiology Study Section (PHY)
Project Start
1980-04-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
16
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Rush University
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Leung, Michael Y K; Cohen, Fredric S (2011) Increasing hydrophobicity of residues in an anti-HIV-1 Env peptide synergistically improves potency. Biophys J 100:1960-8
Markosyan, Ruben M; Cohen, Fredric S (2010) Negative potentials across biological membranes promote fusion by class II and class III viral proteins. Mol Biol Cell 21:2001-12
Markosyan, Ruben M; Leung, Michael Y; Cohen, Fredric S (2009) The six-helix bundle of human immunodeficiency virus Env controls pore formation and enlargement and is initiated at residues proximal to the hairpin turn. J Virol 83:10048-57
Markosyan, Ruben M; Kielian, Margaret; Cohen, Fredric S (2007) Fusion induced by a class II viral fusion protein, semliki forest virus E1, is dependent on the voltage of the target cell. J Virol 81:11218-25
Abrahamyan, Levon G; Mkrtchyan, Samvel R; Binley, James et al. (2005) The cytoplasmic tail slows the folding of human immunodeficiency virus type 1 Env from a late prebundle configuration into the six-helix bundle. J Virol 79:106-15
Mkrtchyan, Samvel R; Markosyan, Ruben M; Eadon, Michael T et al. (2005) Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusion. J Virol 79:11161-9
Markosyan, Ruben M; Cohen, Fredric S; Melikyan, Grigory B (2005) Time-resolved imaging of HIV-1 Env-mediated lipid and content mixing between a single virion and cell membrane. Mol Biol Cell 16:5502-13
Melikyan, G B; Barnard, R J O; Markosyan, R M et al. (2004) Low pH is required for avian sarcoma and leukosis virus Env-induced hemifusion and fusion pore formation but not for pore growth. J Virol 78:3753-62
Markosyan, R M; Bates, P; Cohen, F S et al. (2004) A study of low pH-induced refolding of Env of avian sarcoma and leukosis virus into a six-helix bundle. Biophys J 87:3291-8
Cohen, F S; Melikyan, G B (2004) The energetics of membrane fusion from binding, through hemifusion, pore formation, and pore enlargement. J Membr Biol 199:1-14

Showing the most recent 10 out of 64 publications