Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
7R01GM027731-14
Application #
3274971
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1980-04-01
Project End
1993-03-31
Budget Start
1993-01-01
Budget End
1993-03-31
Support Year
14
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Nur-E-Kamal, Alam; Li, Tsai-Kun; Zhang, Ailing et al. (2003) Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals. J Biol Chem 278:12475-81
Qi, Haiyan; Li, Tsai-Kun; Kuo, Debbie et al. (2003) Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast. J Biol Chem 278:15136-41
Zhou, Nai; Xiao, Hai; Li, Tsai-Kun et al. (2003) DNA damage-mediated apoptosis induced by selenium compounds. J Biol Chem 278:29532-7
Xiao, Hai; Li, Tsai-Kun; Yang, Jin-Ming et al. (2003) Acidic pH induces topoisomerase II-mediated DNA damage. Proc Natl Acad Sci U S A 100:5205-10
Xiao, Hai; Mao, Yong; Desai, Shyamal D et al. (2003) The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway. Proc Natl Acad Sci U S A 100:3239-44
Li, T K; Liu, L F (2001) Tumor cell death induced by topoisomerase-targeting drugs. Annu Rev Pharmacol Toxicol 41:53-77
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Wang, H; Mao, Y; Chen, A Y et al. (2001) Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation. Biochemistry 40:3316-23

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