Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM027939-15
Application #
2175049
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1980-04-01
Project End
1997-05-31
Budget Start
1995-06-01
Budget End
1997-05-31
Support Year
15
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Syntex (USA), Inc.-Research Division
Department
Type
DUNS #
City
Palo Alto
State
CA
Country
United States
Zip Code
94304
Holman, C M; Kan, C C; Gehring, M R et al. (1999) Role of His-224 in the anomalous pH dependence of human stromelysin-1. Biochemistry 38:677-81
Welch, A R; Holman, C M; Huber, M et al. (1996) Understanding the P1' specificity of the matrix metalloproteinases: effect of S1' pocket mutations in matrilysin and stromelysin-1. Biochemistry 35:10103-9
Welch, A R; Holman, C M; Browner, M F et al. (1995) Purification of human matrilysin produced in Escherichia coli and characterization using a new optimized fluorogenic peptide substrate. Arch Biochem Biophys 324:59-64
Springman, E B; Nagase, H; Birkedal-Hansen, H et al. (1995) Zinc content and function in human fibroblast collagenase. Biochemistry 34:15713-20
Netzel-Arnett, S; Salari, A; Goli, U B et al. (1994) Evidence for a triple helix recognition site in the hemopexin-like domains of human fibroblast and neutrophil interstitial collagenases. Ann N Y Acad Sci 732:22-30
Netzel-Arnett, S; Sang, Q X; Moore, W G et al. (1993) Comparative sequence specificities of human 72- and 92-kDa gelatinases (type IV collagenases) and PUMP (matrilysin). Biochemistry 32:6427-32
Angleton, E L; Nagase, H; Birkedal-Hansen, H et al. (1992) Fluorogenic peptide substrates optimized for five human matrix metalloproteinases. Matrix Suppl 1:89-90
French, M F; Bhown, A; Van Wart, H E (1992) Identification of Clostridium histolyticum collagenase hyperreactive sites in type I, II, and III collagens: lack of correlation with local triple helical stability. J Protein Chem 11:83-97
Mookhtiar, K A; Van Wart, H E (1992) Clostridium histolyticum collagenases: a new look at some old enzymes. Matrix Suppl 1:116-26
Devarajan, P; Johnston, J J; Ginsberg, S S et al. (1992) Structure and expression of neutrophil gelatinase cDNA. Identity with type IV collagenase from HT1080 cells. J Biol Chem 267:25228-32

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