Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM028007-17S1
Application #
2561175
Study Section
Biochemistry Study Section (BIO)
Project Start
1980-07-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
17
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Lampert, Thomas J; Kamprad, Nadine; Edwards, Marc et al. (2017) Shear force-based genetic screen reveals negative regulators of cell adhesion and protrusive activity. Proc Natl Acad Sci U S A 114:E7727-E7736
Hoeller, Oliver; Toettcher, Jared E; Cai, Huaqing et al. (2016) G? Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration. PLoS Biol 14:e1002381
Nguyen, H-N; Yang Jr, J-M; Rahdar, M et al. (2015) A new class of cancer-associated PTEN mutations defined by membrane translocation defects. Oncogene 34:3737-43
Santhanam, Balaji; Cai, Huaqing; Devreotes, Peter N et al. (2015) The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium. Nat Commun 6:7551
Yang, Jr-Ming; Nguyen, Hoai-Nghia; Sesaki, Hiromi et al. (2015) Engineering PTEN function: membrane association and activity. Methods 77-78:119-24
Swaney, Kristen F; Borleis, Jane; Iglesias, Pablo A et al. (2015) Novel protein Callipygian defines the back of migrating cells. Proc Natl Acad Sci U S A 112:E3845-54
Nguyen, Hoai-Nghia; Yang, Jr-Ming; Miyamoto, Takafumi et al. (2015) Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN. Sci Rep 5:12600
Gao, Runchi; Zhao, Siwei; Jiang, Xupin et al. (2015) A large-scale screen reveals genes that mediate electrotaxis in Dictyostelium discoideum. Sci Signal 8:ra50
Artemenko, Yulia; Lampert, Thomas J; Devreotes, Peter N (2014) Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes. Cell Mol Life Sci 71:3711-47
Cai, Huaqing; Katoh-Kurasawa, Mariko; Muramoto, Tetsuya et al. (2014) Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer. Science 343:1249531

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