Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM028673-15
Application #
2175242
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1982-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Southern California
Department
Miscellaneous
Type
Schools of Allied Health Profes
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Xu, Guiyan; Kane, David J; Faller, Larry D et al. (2004) The role of loop 6/7 in folding and functional performance of Na,K-ATPase. J Biol Chem 279:45594-602
Xu, G; Farley, R A; Kane, D J et al. (2003) Site-directed mutagenesis of amino acids in the cytoplasmic loop 6/7 of Na,K-ATPase. Ann N Y Acad Sci 986:96-100
Muller-Ehmsen, Jochen; McDonough, Alicia A; Farley, Robert A et al. (2002) Sodium pump isoform expression in heart failure: implication for treatment. Basic Res Cardiol 97 Suppl 1:I25-30
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Muller-Ehmsen, J; Juvvadi, P; Thompson, C B et al. (2001) Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when expressed separately in yeast cells. Am J Physiol Cell Physiol 281:C1355-64
Farley, R A; Schreiber, S; Wang, S G et al. (2001) A hybrid between Na+,K+-ATPase and H+,K+-ATPase is sensitive to palytoxin, ouabain, and SCH 28080. J Biol Chem 276:2608-15
Wang, J; Velotta, J B; McDonough, A A et al. (2001) All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides. Am J Physiol Cell Physiol 281:C1336-43
Kutchai, H; Geddis, L M; Farley, R A (2000) Effects of local anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res 41:7-Jan
Tran, C M; Farley, R A (1999) Catalytic activity of an isolated domain of Na,K-ATPase expressed in Escherichia coli. Biophys J 77:258-66
Kutchai, H; Geddis, L M; Farley, R A (1999) Effects of general anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res 40:469-73

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