Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM029379-16
Application #
2175496
Study Section
Molecular Biology Study Section (MBY)
Project Start
1981-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Arts and Sciences
DUNS #
071723621
City
Cambridge
State
MA
Country
United States
Zip Code
02138
Zhou, Rui; Silverman, Neal; Hong, Mei et al. (2005) The role of ubiquitination in Drosophila innate immunity. J Biol Chem 280:34048-55
Stoven, Svenja; Silverman, Neal; Junell, Anna et al. (2003) Caspase-mediated processing of the Drosophila NF-kappaB factor Relish. Proc Natl Acad Sci U S A 100:5991-6
Silverman, Neal; Zhou, Rui; Erlich, Rachel L et al. (2003) Immune activation of NF-kappaB and JNK requires Drosophila TAK1. J Biol Chem 278:48928-34
Rutschmann, S; Jung, A C; Zhou, R et al. (2000) Role of Drosophila IKK gamma in a toll-independent antibacterial immune response. Nat Immunol 1:342-7
Silverman, N; Zhou, R; Stoven, S et al. (2000) A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev 14:2461-71
Abel, T; Michelson, A M; Maniatis, T (1993) A Drosophila GATA family member that binds to Adh regulatory sequences is expressed in the developing fat body. Development 119:623-33
Winick, J; Abel, T; Leonard, M W et al. (1993) A GATA family transcription factor is expressed along the embryonic dorsoventral axis in Drosophila melanogaster. Development 119:1055-65
Abel, T; Bhatt, R; Maniatis, T (1992) A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements. Genes Dev 6:466-80
Falb, D; Maniatis, T (1992) A conserved regulatory unit implicated in tissue-specific gene expression in Drosophila and man. Genes Dev 6:454-65
Falb, D; Maniatis, T (1992) Drosophila transcriptional repressor protein that binds specifically to negative control elements in fat body enhancers. Mol Cell Biol 12:4093-103

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