Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM029487-16
Application #
2175538
Study Section
Molecular Biology Study Section (MBY)
Project Start
1981-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Luse, Donal S (2013) Promoter clearance by RNA polymerase II. Biochim Biophys Acta 1829:63-8
Luse, Donal S (2012) Rethinking the role of TFIIF in transcript initiation by RNA polymerase II. Transcription 3:156-9
?abart, Pavel; Luse, Donal S (2012) Inactivated RNA polymerase II open complexes can be reactivated with TFIIE. J Biol Chem 287:961-7
Cabart, Pavel; Ujvari, Andrea; Pal, Mahadeb et al. (2011) Transcription factor TFIIF is not required for initiation by RNA polymerase II, but it is essential to stabilize transcription factor TFIIB in early elongation complexes. Proc Natl Acad Sci U S A 108:15786-91
Újvári, Andrea; Pal, Mahadeb; Luse, Donal S (2011) The functions of TFIIF during initiation and transcript elongation are differentially affected by phosphorylation by casein kinase 2. J Biol Chem 286:23160-7
Ujvari, Andrea; Luse, Donal S (2006) RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit. Nat Struct Mol Biol 13:49-54
Pal, Mahadeb; Ponticelli, Alfred S; Luse, Donal S (2005) The role of the transcription bubble and TFIIB in promoter clearance by RNA polymerase II. Mol Cell 19:101-10
Hawryluk, Peter J; Ujvari, Andrea; Luse, Donal S (2004) Characterization of a novel RNA polymerase II arrest site which lacks a weak 3' RNA-DNA hybrid. Nucleic Acids Res 32:1904-16
Ujvari, Andrea; Luse, Donal S (2004) Newly Initiated RNA encounters a factor involved in splicing immediately upon emerging from within RNA polymerase II. J Biol Chem 279:49773-9
Pal, Mahadeb; Luse, Donal S (2003) The initiation-elongation transition: lateral mobility of RNA in RNA polymerase II complexes is greatly reduced at +8/+9 and absent by +23. Proc Natl Acad Sci U S A 100:5700-5

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