Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM030105-14
Application #
2175700
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1982-02-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Austin
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Austin
State
TX
Country
United States
Zip Code
78712
Almrud, J J; Oliveira, M A; Kern, A D et al. (2000) Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding. J Mol Biol 295:16-Jul
Stamps, S L; Taylor, A B; Wang, S C et al. (2000) Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants. Biochemistry 39:9671-8
Knapp, J E; Carroll, D; Lawson, J E et al. (2000) Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferase. Protein Sci 9:37-48
Vitali, J; Carroll, D; Chaudhry, R G et al. (1999) Three-dimensional structure of the Gly121Tyr dimeric form of ornithine decarboxylase from Lactobacillus 30a. Acta Crystallogr D Biol Crystallogr 55:1978-85
Taylor, A B; Johnson Jr, W H; Czerwinski, R M et al. (1999) Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition. Biochemistry 38:7444-52
Kern, A D; Oliveira, M A; Coffino, P et al. (1999) Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases. Structure 7:567-81
Taylor, A B; Czerwinski, R M; Johnson Jr, W H et al. (1998) Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2-oxo-3-pentynoate at 2.4 A resolution: analysis and implications for the mechanism of inactivation and catalysis. Biochemistry 37:14692-700
Kitto, G B; Thomas, P W; Hackert, M L (1998) Evolution of cooperativity in hemoglobins: what can invertebrate hemoglobins tell us? J Exp Zool 282:120-6
Oliveira, M A; Carroll, D; Davidson, L et al. (1997) The GTP effector site of ornithine decarboxylase from Lactobacillus 30a: kinetic and structural characterization. Biochemistry 36:16147-54
Kern, A; Oliveira, M A; Chang, N L et al. (1996) Crystallization of a mammalian ornithine decarboxylase. Proteins 24:266-8

Showing the most recent 10 out of 24 publications