Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM030415-15
Application #
2175809
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1982-06-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Asahara, Hitomi; Li, Ying; Fuss, Jill et al. (2003) Stimulation of human DNA polymerase epsilon by MDM2. Nucleic Acids Res 31:2451-9
Fuss, Jill; Linn, Stuart (2002) Human DNA polymerase epsilon colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase. J Biol Chem 277:8658-66
Takemura, M; Yamamoto, T; Kitagawa, M et al. (2001) Stimulation of DNA polymerase alpha activity by cdk2-phosphorylated Rb protein. Biochem Biophys Res Commun 282:984-90
Li, Y; Pursell, Z F; Linn, S (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275:23247-52
Liu, W; Linn, S (2000) Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis. Nucleic Acids Res 28:4180-8
Vlatkovic, N; Guerrera, S; Li, Y et al. (2000) MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon. Nucleic Acids Res 28:3581-6
Shiyanov, P; Hayes, S A; Donepudi, M et al. (1999) The naturally occurring mutants of DDB are impaired in stimulating nuclear import of the p125 subunit and E2F1-activated transcription. Mol Cell Biol 19:4935-43
Li, Y; Asahara, H; Patel, V S et al. (1997) Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon. J Biol Chem 272:32337-44
Jessberger, R; Chui, G; Linn, S et al. (1996) Analysis of the mammalian recombination protein complex RC-1. Mutat Res 350:217-27
Chui, G; Linn, S (1995) Further characterization of HeLa DNA polymerase epsilon. J Biol Chem 270:7799-808

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