Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM030614-13
Application #
2175856
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1983-03-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Minca, Eugen C; Kowalski, David (2011) Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulation. Nucleic Acids Res 39:2610-23
Minca, Eugen C; Kowalski, David (2010) Multiple Rad5 activities mediate sister chromatid recombination to bypass DNA damage at stalled replication forks. Mol Cell 38:649-61
Kowalski, David; Pendyala, Lakshmi; Daignan-Fornier, Bertrand et al. (2008) Dysregulation of purine nucleotide biosynthesis pathways modulates cisplatin cytotoxicity in Saccharomyces cerevisiae. Mol Pharmacol 74:1092-100
Huang, Ruea-Yea; Kowalski, David; Minderman, Hans et al. (2007) Small ubiquitin-related modifier pathway is a major determinant of doxorubicin cytotoxicity in Saccharomyces cerevisiae. Cancer Res 67:765-72
Huang, Ruea-Yea; Eddy, Martha; Vujcic, Marija et al. (2005) Genome-wide screen identifies genes whose inactivation confer resistance to cisplatin in Saccharomyces cerevisiae. Cancer Res 65:5890-7
Dziegielewska, Barbara; Kowalski, David; Beerman, Terry A (2004) SV40 DNA replication inhibition by the monofunctional DNA alkylator Et743. Biochemistry 43:14228-37
Huang, Yanlin; Kowalski, David (2004) PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability. BMC Bioinformatics 5:134
Huang, Yanlin; Kowalski, David (2003) WEB-THERMODYN: Sequence analysis software for profiling DNA helical stability. Nucleic Acids Res 31:3819-21
Wang, Y; Vujcic, M; Kowalski, D (2001) DNA replication forks pause at silent origins near the HML locus in budding yeast. Mol Cell Biol 21:4938-48
Wang, Y; Beerman, T A; Kowalski, D (2001) Antitumor drug adozelesin differentially affects active and silent origins of DNA replication in yeast checkpoint kinase mutants. Cancer Res 61:3787-94

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