Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM031480-14
Application #
2176145
Study Section
Molecular Biology Study Section (MBY)
Project Start
1990-08-01
Project End
1999-11-30
Budget Start
1995-12-15
Budget End
1996-11-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Huang, Hon-Ren; Rowe, Claire E; Mohr, Sabine et al. (2005) The splicing of yeast mitochondrial group I and group II introns requires a DEAD-box protein with RNA chaperone function. Proc Natl Acad Sci U S A 102:163-8
Dickson, Lorna; Connell, Stuart; Huang, Hon-Ren et al. (2004) Abortive transposition by a group II intron in yeast mitochondria. Genetics 168:77-87
Schafer, Bernd; Gan, Lin; Perlman, Philip S (2003) Reverse transcriptase and reverse splicing activities encoded by the mobile group II intron cobI1 of fission yeast mitochondrial DNA. J Mol Biol 329:191-206
Huang, Hon-Ren; Chao, Michael Y; Armstrong, Barbara et al. (2003) The DIVa maturase binding site in the yeast group II intron aI2 is essential for intron homing but not for in vivo splicing. Mol Cell Biol 23:8809-19
Podar, Mircea; Mullineaux, Lauren; Huang, Hon-Ren et al. (2002) Bacterial group II introns in a deep-sea hydrothermal vent environment. Appl Environ Microbiol 68:6392-8
Dickson, L; Huang, H R; Liu, L et al. (2001) Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites. Proc Natl Acad Sci U S A 98:13207-12
Chu, V T; Adamidi, C; Liu, Q et al. (2001) Control of branch-site choice by a group II intron. EMBO J 20:6866-76
Zhang, Y; Bell, A; Perlman, P S et al. (2000) Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae. RNA 6:937-51
Eskes, R; Liu, L; Ma, H et al. (2000) Multiple homing pathways used by yeast mitochondrial group II introns. Mol Cell Biol 20:8432-46
Podar, M; Perlman, P S (1999) Photocrosslinking of 4-thio uracil-containing RNAs supports a side-by-side arrangement of domains 5 and 6 of a group II intron. RNA 5:318-29

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