Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM031546-14S1
Application #
1033248
Study Section
Endocrinology Study Section (END)
Project Start
1983-01-01
Project End
1998-07-31
Budget Start
1995-08-01
Budget End
1996-07-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Genetics
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Ning, Y M; Robins, D M (1999) AML3/CBFalpha1 is required for androgen-specific activation of the enhancer of the mouse sex-limited protein (Slp) gene. J Biol Chem 274:30624-30
Scheller, A; Hughes, E; Golden, K L et al. (1998) Multiple receptor domains interact to permit, or restrict, androgen-specific gene activation. J Biol Chem 273:24216-22
Scarlett, C O; Scheller, A; Thompson, E et al. (1997) Involvement of an octamer-like sequence within a crucial region of the androgen-dependent Slp enhancer. DNA Cell Biol 16:45-57
Nelson, S A; Robins, D M (1997) Regulatory capacity of an androgen-specific enhancer of the mouse Slp gene in transgenic mice. Mol Cell Endocrinol 133:89-97
Nelson, S A; Robins, D M (1997) Two distinct mechanisms elicit androgen-dependent expression of the mouse sex-limited protein gene. Mol Endocrinol 11:460-9
Burgos-Trinidad, M; Youngblood, G L; Maroto, M R et al. (1997) Repression of cAMP-induced expression of the mouse P450 17 alpha-hydroxylase/C17-20 lyase gene (Cyp17) by androgens. Mol Endocrinol 11:87-96
Scarlett, C O; Robins, D M (1995) In vivo footprinting of an androgen-dependent enhancer reveals an accessory element integral to hormonal response. Mol Endocrinol 9:413-23
Adler, A J; Scheller, A; Robins, D M (1993) The stringency and magnitude of androgen-specific gene activation are combinatorial functions of receptor and nonreceptor binding site sequences. Mol Cell Biol 13:6326-35
Adler, A J; Danielsen, M; Robins, D M (1992) Androgen-specific gene activation via a consensus glucocorticoid response element is determined by interaction with nonreceptor factors. Proc Natl Acad Sci U S A 89:11660-3
Cox, B J; Robins, D M (1988) Tissue-specific variation in C4 and Slp gene regulation. Nucleic Acids Res 16:6857-70

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