Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM032691-14A2S1
Application #
6833642
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Program Officer
Chin, Jean
Project Start
1983-03-01
Project End
2007-04-30
Budget Start
2003-05-01
Budget End
2004-04-30
Support Year
14
Fiscal Year
2004
Total Cost
$6,878
Indirect Cost
Name
Syracuse University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
002257350
City
Syracuse
State
NY
Country
United States
Zip Code
13244
Ouyang, Wei; Okaine, Stephen; McPike, Mark P et al. (2013) Probing the RNA binding surface of the HIV-1 nucleocapsid protein by site-directed mutagenesis. Biochemistry 52:3358-68
Mohammad, Mohammad M; Iyer, Raghuvaran; Howard, Khalil R et al. (2012) Engineering a rigid protein tunnel for biomolecular detection. J Am Chem Soc 134:9521-31
Athavale, Shreyas S; Ouyang, Wei; McPike, Mark P et al. (2010) Effects of the nature and concentration of salt on the interaction of the HIV-1 nucleocapsid protein with SL3 RNA. Biochemistry 49:3525-33
DeCiantis, Christopher L; Jensen, Danielle K; Hudson, Bruce S et al. (2007) A nucleic acid switch triggered by the HIV-1 nucleocapsid protein. Biochemistry 46:9164-73
Rivera, Sharon A; Hudson, Bruce S (2006) Rapid exchange luminescence: nitroxide quenching and implications for sensor applications. J Am Chem Soc 128:18-9
McPike, Mark P; Goodisman, Jerry; Dabrowiak, James C (2004) Specificity of neomycin analogues bound to the packaging region of human immunodeficiency virus type 1 RNA. Bioorg Med Chem 12:1835-43
Cavaluzzi, Michael J; Borer, Philip N (2004) Revised UV extinction coefficients for nucleoside-5'-monophosphates and unpaired DNA and RNA. Nucleic Acids Res 32:e13
Yuan, YiQiong; Kerwood, Deborah J; Paoletti, Andrew C et al. (2003) Stem of SL1 RNA in HIV-1: structure and nucleocapsid protein binding for a 1 x 3 internal loop. Biochemistry 42:5259-69
McPike, Mark P; Goodisman, Jerry; Dabrowiak, James C (2002) Footprinting and circular dichroism studies on paromomycin binding to the packaging region of human immunodeficiency virus type-1. Bioorg Med Chem 10:3663-72
Shubsda, Michael F; Paoletti, Andrew C; Hudson, Bruce S et al. (2002) Affinities of packaging domain loops in HIV-1 RNA for the nucleocapsid protein. Biochemistry 41:5276-82

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