Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM032833-13
Application #
2176751
Study Section
Biochemistry Study Section (BIO)
Project Start
1983-12-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Biochemistry
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Song, Jimyeong; Kemp, Michael G; Choi, Jun-Hyuk (2017) Detection of the Excised, Damage-containing Oligonucleotide Products of Nucleotide Excision Repair in Human Cells. Photochem Photobiol 93:192-198
Kemp, Michael G (2017) Crosstalk Between Apoptosis and Autophagy: Environmental Genotoxins, Infection, and Innate Immunity. J Cell Death 9:1179670716685085
Kemp, Michael G; Hu, Jinchuan (2017) PostExcision Events in Human Nucleotide Excision Repair. Photochem Photobiol 93:178-191
Canturk, Fazile; Karaman, Muhammet; Selby, Christopher P et al. (2016) Nucleotide excision repair by dual incisions in plants. Proc Natl Acad Sci U S A 113:4706-10
Adar, Sheera; Hu, Jinchuan; Lieb, Jason D et al. (2016) Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis. Proc Natl Acad Sci U S A 113:E2124-33
Kemp, Michael G; Sancar, Aziz (2016) ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress. J Biol Chem 291:9330-42
Gaddameedhi, Shobhan; Selby, Christopher P; Kemp, Michael G et al. (2015) The circadian clock controls sunburn apoptosis and erythema in mouse skin. J Invest Dermatol 135:1119-1127
Kemp, Michael G; Lindsey-Boltz, Laura A; Sancar, Aziz (2015) UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1). J Biol Chem 290:12184-94
Lindsey-Boltz, Laura A; Kemp, Michael G; Capp, Christopher et al. (2015) RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling. Cell Cycle 14:99-108
Choi, Jun-Hyuk; Kim, So-Young; Kim, Sook-Kyung et al. (2015) An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells: NUCLEOTIDE EXCISION REPAIR, DNA DAMAGE CHECKPOINT, AND APOPTOSIS. J Biol Chem 290:28812-21

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