Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM033138-22
Application #
2176869
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1983-07-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Pharmacology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Chu, Uyen B; Ramachandran, Subramaniam; Hajipour, Abdol R et al. (2013) Photoaffinity labeling of the sigma-1 receptor with N-[3-(4-nitrophenyl)propyl]-N-dodecylamine: evidence of receptor dimers. Biochemistry 52:859-68
Ruoho, Arnold E; Chu, Uyen B; Ramachandran, Subramaniam et al. (2012) The ligand binding region of the sigma-1 receptor: studies utilizing photoaffinity probes, sphingosine and N-alkylamines. Curr Pharm Des 18:920-9
Chu, Uyen B; Hajipour, Abdol R; Ramachandran, Subramaniam et al. (2011) Characterization of interactions of 4-nitrophenylpropyl-N-alkylamine with ýý receptors. Biochemistry 50:7568-78
Guo, Lian-Wang; Ruoho, Arnold E (2011) N-terminal half of the cGMP phosphodiesterase gamma-subunit contributes to stabilization of the GTPase-accelerating protein complex. J Biol Chem 286:15260-7
Mavlyutov, Timur A; Nickells, Robert W; Guo, Lian-Wang (2011) Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor. Mol Vis 17:1034-43
Guo, Lian-Wang; Hajipour, Abdol R; Ruoho, Arnold E (2010) Complementary interactions of the rod PDE6 inhibitory subunit with the catalytic subunits and transducin. J Biol Chem 285:15209-19
Zahmatkesh, Saeed; Hajipour, Abdol R (2010) Microwave-assisted synthesis and characterization of optically active poly (ester-imide)s incorporating L-alanine. Amino Acids 38:1253-60
Chu, Uyen B; Song, Jikui; Mavlyutov, Timur A et al. (2010) In vitro interaction of tubulin with the photoreceptor cGMP phosphodiesterase gamma-subunit. Neurosci Lett 482:225-9
Hajipour, Abdol R; Zahmatkesh, Saeed; Roosta, Parniyan et al. (2009) Synthesis and characterization of new optically active poly(azo-ester-imide)s via interfacial polycondensation. Amino Acids 36:511-8
Song, Jikui; Guo, Lian-Wang; Muradov, Hakim et al. (2008) Intrinsically disordered gamma-subunit of cGMP phosphodiesterase encodes functionally relevant transient secondary and tertiary structure. Proc Natl Acad Sci U S A 105:1505-10

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