Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM033523-13
Application #
2177046
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1984-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Zeitlin, Samantha G; Patel, Sheetal; Kavli, Bodil et al. (2005) Xenopus CENP-A assembly into chromatin requires base excision repair proteins. DNA Repair (Amst) 4:760-72
Harvey, Kevin J; Newport, John (2003) Metazoan origin selection: origin recognition complex chromatin binding is regulated by CDC6 recruitment and ATP hydrolysis. J Biol Chem 278:48524-8
Harvey, Kevin J; Newport, John (2003) CpG methylation of DNA restricts prereplication complex assembly in Xenopus egg extracts. Mol Cell Biol 23:6769-79
Yamaguchi, Ryuji; Newport, John (2003) A role for Ran-GTP and Crm1 in blocking re-replication. Cell 113:115-25
Hekmat-Nejad, M; You, Z; Yee, M C et al. (2000) Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint. Curr Biol 10:1565-73
Michael, W M; Ott, R; Fanning, E et al. (2000) Activation of the DNA replication checkpoint through RNA synthesis by primase. Science 289:2133-7
Lin, X H; Walter, J; Scheidtmann, K et al. (1998) Protein phosphatase 2A is required for the initiation of chromosomal DNA replication. Proc Natl Acad Sci U S A 95:14693-8
Walter, J; Sun, L; Newport, J (1998) Regulated chromosomal DNA replication in the absence of a nucleus. Mol Cell 1:519-29
Howe, J A; Newport, J W (1996) A developmental timer regulates degradation of cyclin E1 at the midblastula transition during Xenopus embryogenesis. Proc Natl Acad Sci U S A 93:2060-4
Guadagno, T M; Newport, J W (1996) Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity. Cell 84:73-82

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