Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM033689-12
Application #
2177095
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1984-07-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Iowa
Department
Biochemistry
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Lee, Cho-Yin; Lou, Jizhong; Wen, Kuo-Kuang et al. (2016) Regulation of actin catch-slip bonds with a RhoA-formin module. Sci Rep 6:35058
Wen, Kuo-Kuang; McKane, Melissa; Stokasimov, Ema et al. (2011) Mutant profilin suppresses mutant actin-dependent mitochondrial phenotype in Saccharomyces cerevisiae. J Biol Chem 286:41745-57
Stark, Benjamin C; Wen, Kuo-Kuang; Allingham, John S et al. (2011) Functional adaptation between yeast actin and its cognate myosin motors. J Biol Chem 286:30384-92
Kudryashov, Dmitri S; Grintsevich, Elena E; Rubenstein, Peter A et al. (2010) A nucleotide state-sensing region on actin. J Biol Chem 285:25591-601
Wen, Kuo-Kuang; McKane, Melissa; Stokasimov, Ema et al. (2010) A potential yeast actin allosteric conduit dependent on hydrophobic core residues val-76 and trp-79. J Biol Chem 285:21185-94
Scoville, Damon; Stamm, John D; Altenbach, Christian et al. (2009) Effects of binding factors on structural elements in F-actin. Biochemistry 48:370-8
Stokasimov, Ema; Rubenstein, Peter A (2009) Actin isoform-specific conformational differences observed with hydrogen/deuterium exchange and mass spectrometry. J Biol Chem 284:25421-30
Wen, Kuo-Kuang; Rubenstein, Peter A; DeMali, Kris A (2009) Vinculin nucleates actin polymerization and modifies actin filament structure. J Biol Chem 284:30463-73
Stokasimov, Ema; McKane, Melissa; Rubenstein, Peter A (2008) Role of intermonomer ionic bridges in the stabilization of the actin filament. J Biol Chem 283:34844-54
Wen, Kuo-Kuang; McKane, Melissa; Houtman, Jon C D et al. (2008) Control of the ability of profilin to bind and facilitate nucleotide exchange from G-actin. J Biol Chem 283:9444-53

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